Zona pellucida is required for oocyte actin cortex and oocyte-somatic cell interactions during oocyte growth.

Shoujing Liang, Weixi Xiang, Ruping Quan, Jiayu Su, Chao Lv, Hualin Huang, Hongmei Xiao

Abstract read

In one paragraph

Article in Cell death discovery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shoujing LiangInstitute of Reproductive and Stem Cell Engineering, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.ORCID http://orcid.org/0000-0002-3759-8718

Weixi XiangInstitute of Reproductive and Stem Cell Engineering, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.

Ruping QuanInstitute of Reproductive and Stem Cell Engineering, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.

Jiayu SuInstitute of Reproductive and Stem Cell Engineering, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.

Chao LvDepartment of Reproductive Medicine Center, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Hualin HuangReproductive Medicine Center, Department of Obstetrics and Gynecology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

Hongmei XiaoInstitute of Reproductive and Stem Cell Engineering, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China. hmxiao@csu.edu.cn.ORCID http://orcid.org/0000-0002-8121-9498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structural defects in the zona pellucida (ZP), caused by mutations in ZP genes, are a recognized cause of female infertility; however, their pathogenic mechanisms are not fully understood. Here, we investigated how two distinct ZP defects (complete absence and thinning) compromise fertility using Zp1

Identifiers

PMID42009647

DOI10.1038/s41420-026-03124-9

PMCPMC13230721

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.