Evidence map›Paper›PMID 42010106›Full record

ArticleJournal of general internal medicine2026

Upstream Drivers of Poor Cardiovascular Health Among Black and White Americans.

Nila Uthirasamy, Joanna Bryan, Ghislaine Jumonville, Kate Yao Berg, Tyson Brown, Monika M Safford, Laura C Pinheiro

Abstract read
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In one paragraph

Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nila UthirasamyWeill Cornell Medicine, New York, NY, USA. niu4004@med.cornell.edu.ORCID http://orcid.org/0000-0002-3300-3924
Joanna BryanWeill Cornell Medicine, New York, NY, USA.
Ghislaine JumonvilleWeill Cornell Medicine, New York, NY, USA.
Kate Yao BergWeill Cornell Medicine, New York, NY, USA.
Tyson BrownDuke University, Durham, NC, USA.
Monika M SaffordWeill Cornell Medicine, New York, NY, USA.
Laura C PinheiroWeill Cornell Medicine, New York, NY, USA.

Funding

Structural Racism and Cardiovascular Outcomes Among Cancer SurvivorsR37CA288492 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Laura C Pinheiro · 2024 to 2026
$1.9M
NCI NIH HHS R37 CA288492
6 · The paper itself

Abstract

BACKGROUND AND

objectiveSince cardiovascular health (CVH) precedes cardiovascular disease (CVD) outcomes, our study examines associations between state-level structural racism and CVH among Black and White participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. DESIGN AND

participantsA cross-sectional analysis of baseline REGARDS data, a national prospective cohort of 30,239 Black and White adults, 45+ years, enrolled from 2003 to 2007 and followed for 15+ years. MAIN MEASURES: CVH, the primary outcome, was operationalized using Life's Essential 8 (LE8)-physical activity, BMI, blood pressure, diet, cholesterol, smoking, glucose, sleep-with each component scored 0-100 and composite scores categorized as poor (< 50), intermediate (50-79), ideal (≥ 80). State-level structural racism measures (dichotomized at the median), created using the 2000 U.S. Census, Vera Institute, U.S. Census Current Population Survey, included Black:White ratios (B:W) for jail incarceration, residential segregation, economic status, education, employment, and health insurance. Participants with > 7 LE8 components and complete structural racism measures were included. All analyses were race-stratified. Ordinal logistic regression models were used to estimate associations and calculate adjusted proportional odds ratios and 95% confidence intervals. KEY

resultsIn total, 24,811 participants were included. Average LE8 scores were significantly lower among Black than White participants (56 vs. 64; p < 0.001). Among Black participants, higher odds of low CVH were observed in states with greater structural racism: high B:W unemployment (OR = 1.41, 95% CI 1.23-1.61), residential segregation (1.39, 1.26-1.53), education (1.37, 1.20-1.56), poverty (1.22, 1.11-1.35), uninsured status (1.12, 1.02-1.22). White adults in high structural racism states also had higher odds of low CVH for unemployment (1.16, 1.04-1.29), segregation (1.22, 1.13-1.30), education (1.12, 1.03-1.21).

conclusionsBlack participants in high structural racism states were at increased risk of poor CVH across measures of structural racism. White residents of these states were also at increased risk of poor CVH for fewer measures. Policy addressing structural factors like segregation and unemployment may help reduce Black-White CVH inequities.

Indexed as

cardiovascular healthhealth disparitieshealth inequity

Identifiers

PMID42010106

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.