ArticleEJNMMI physics2026
AI-based synthetic CT attenuation correction enables reliable quantitative SPECT in unilateral condylar hyperplasia.
Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeUnilateral condylar hyperplasia (UCH) is a rare mandibular growth disorder in which accurate assessment of condylar metabolic activity is essential for surgical decision-making. Quantitative
methodsThis retrospective study included 14 patients with UCH who underwent
resultsVisual evaluation revealed no relevant differences in image quality between the two reconstructions. Relative uptake fractions normalized to the summed condylar activity showed good agreement between methods. Clivus-normalized ratios demonstrated a small positive bias.
conclusionAI-generated SyCT provides attenuation correction comparable to CTAC for clinically relevant relative condylar uptake assessment in UCH, supporting its use as a low-radiation alternative for quantitative mandibular SPECT imaging.
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