ArticleTrials2026
Trauma-informed intervention to reduce substance use and to support community transition [TRUST]: Study protocol for a type 1 effectiveness-implementation hybrid trial to reduce overdose risk among justice-involved women.
Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06651528 (An Innovative, Trauma-informed Approach for Reducing Overdose Risk Among Women Re-entering the Community From Prison), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Innovative, Trauma-informed Approach for Reducing Overdose Risk Among Women Re-entering the Community From Prison
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundThe integration of trauma-informed interventions for justice-involved women into SUD treatment is a key strategy for mitigating overdose risk. Coupling the unique overdose risk factors for women with their histories of violent victimization and related trauma, overdose intervention approaches for women must be engaging, targeted, and trauma-informed.
methodsThis study utilizes a type 1 hybrid effectiveness and implementation trial to examine an innovative trauma-inforned intervention for justice-involved women (N = 264) in corrections-based substance use treatment during the transition from jail to the community. By equipping women with relational, coping, and emotional regulation skills to manage trauma-related reactions, they are expected to gain the tools and strategies needed to reduce their risk of returning to substance use after release. DISCUSSION: The importance of knowledge gained through this study is grounded in the national public health crisis associated with overdose deaths, largely associated with the opioid epidemic, but also related to unique issues faced by women and the limited, targeted, trauma-informed overdose prevention interventions for this population. This study that has the potential to significantly reduce overdose risk among justice-involved women with a history of violent victimization and related trauma.
trial registrationThis study is registered in ClinicalTrials.gov under protocol identifier-NCT06651528 with an original submission date of October 16, 2024, and updated December 12, 2025 (clinicaltrials.gov/study/NCT06651528).
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