Evidence map›Paper›PMID 42010688›Full record

ReviewNutrition & metabolism2026

Mechanisms of weight recurrence after bariatric surgery.

Rajiv Kumar Yadav, Ye Zhang, You Lv, Songyang Liu, Jiaxing Yang, Yao Wang, Xiaokun Gang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrition & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rajiv Kumar YadavDepartment of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, 130021, Jilin, China.
Ye ZhangDepartment of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, 130021, Jilin, China.
You LvDepartment of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, 130021, Jilin, China.
Songyang LiuDepartment of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, China.
Jiaxing YangDepartment of Gastrocolorectal Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, China.
Yao WangDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, 130041, China. wangyao918@163.com.
Xiaokun GangDepartment of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, 130021, Jilin, China. gangxk@jlu.edu.cn.

Funding

Science and Technology Department, and National Natural Science Fund, Jilin Province, China YDZJ202402042CXJD, YDZJ202401410ZYTS, 82272993, 2022-CXM-06, 81972372
6 · The paper itself

Abstract

Obesity is a major health concern in today’s growing population, significantly raising the risk of disease and death. Bariatric surgery is the most effective treatment for obesity and its related conditions. However, weight recurrence remains a common issue post-surgery. This study aims to understand the mechanisms of Weight recurrence after Bariatric surgery, other than anatomic surgery failure. Weight recurrence may result from various factors, including genetic predisposition, psychological and behavioral influences, neuroendocrine changes, alterations in the gut microbiome, bile acid signaling, and post-surgery hypoglycemia. Prevention and management strategies include lifestyle modifications, mental health support, pharmacotherapy, and, in some cases, revision surgery. This study explores the controversial hormonal changes involved in weight recurrence, as well as the roles of gut microbiota, bile acid signaling, and genetic factors. Additionally, the study highlights several preventable factors that are crucial for maintaining long-term weight loss and minimizing weight recurrence after bariatric surgery. By gaining insight into these hormonal changes and other contributing factors, we can implement effective preventive measures and medical treatments to enhance long-term weight loss success and improve patients’ quality of life. Nonetheless, further research is needed to fully understand the contributions of bile acid signaling and gut microbiota in the process.

Indexed as

Bariatric surgeryDiabetesInsulin resistanceObesityWeight lossWeight recurrence

Identifiers

PMID42010688
PMCPMC13231773

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.