Evidence map›Paper›PMID 42010844›Full record

ArticleAustralasian journal on ageing2026

Examining HbA1c in Frail Older Adults: A Linked Data Cohort Study.

Gideon Meyerowitz-Katz, Julee McDonagh, Scott William, Reejamol John, Tien-Ming Hng, Mark McLean, Mary Bul, Richard I Lindley, Caleb Ferguson

Abstract read
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In one paragraph

Article in Australasian journal on ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gideon Meyerowitz-KatzFaculty of Science, Medicine and Health, School of Nursing, University of Wollongong, Liverpool, Australia.
Julee McDonaghFaculty of Science, Medicine and Health, School of Nursing, University of Wollongong, Liverpool, Australia.
Scott WilliamFaculty of Science, Medicine and Health, School of Nursing, University of Wollongong, Liverpool, Australia.
Reejamol JohnCentre for Chronic and Complex Care Research, Western Sydney Local Health District, Blacktown Hospital, Blacktown, Australia.
Tien-Ming HngDepartment of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, Australia.
Mark McLeanResearch and Education Network, Westmead Hospital Campus, Westmead, Australia.
Mary BulCentre for Chronic and Complex Care Research, Western Sydney Local Health District, Blacktown Hospital, Blacktown, Australia.
Richard I LindleySydney Medical School, Faculty of Medicine and Health, University of Sydney, Camperdown, Australia.
Caleb FergusonFaculty of Science, Medicine and Health, School of Nursing, University of Wollongong, Liverpool, Australia.

Funding

Estate of Frank Harvey SmithWestern Sydney Local Health District
6 · The paper itself

Abstract

objectiveDiabetes and frailty pose a significant issue for society. Previous research has shown a mixed relationship between diabetes and frailty in older people, indicating a complex interrelationship. The aim of this study was to examine the association between routinely collected HbA1c testing data and frailty in a large cohort from Western Sydney.

methodsData from the Western Sydney Frailty Registry Study were linked to the Blacktown and Mount Druitt hospital HbA1c testing datasets. These datasets include information on patient outcomes, pathological metrics, hospitalisation indicators, and a range of morbidity and demographic information. This was then analysed in Stata using multivariable regression.

resultsDiabetes was more common in frail patients than in pre-frail or non-frail patients. Those with both diabetes and frailty did not have an increased risk of death or rehospitalisation in age and sex corrected analyses (OR: 0.66, 95% CI: 0.36-1.21 and 0.90, 95% CI: 0.37-2.17, respectively) compared to those with frailty alone. There was a reduced risk of death associated with higher HbA1c for frail people (OR: 0.58, 95% CI: 0.37-0.90).

conclusionsThere is a complex interrelationship between diabetes and frailty. For frail people with diabetes, there are important lessons for management. These include the possibility that HbA1c is not a useful metric and that overtreatment with hypoglycaemic agents must be considered.

Indexed as

Diabetes MellitusFrail ElderlyFrailtyGlycated HemoglobinAgedAged, 80 and overAge FactorsBiomarkersFemaleGeriatric AssessmentHumansLogistic ModelsMaleMultivariate AnalysisNew South WalesOdds RatioBiomarkersGlycated Hemoglobinhemoglobin A1c protein, humanageddiabetes mellitusfrailtyglycated haemoglobinmultimorbidity

Identifiers

PMID42010844
PMCPMC13096676

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.