Evidence map›Paper›PMID 42011007›Full record

ArticleStatistics in medicine2026

Novel Influence Diagnostics in Multistate Models for Breast Cancer.

Valeria Leiva-Yamaguchi, Alejandra Tapia, Manuel Galea, Oscar M Rueda

Erratum issuedAbstract read
In one paragraph

Article in Statistics in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Valeria Leiva-YamaguchiMRC Biostatistics, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0009-0001-1157-7943
Alejandra TapiaFacultad de Matemáticas, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0003-0762-7618
Manuel GaleaFacultad de Matemáticas, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0001-9819-5843
Oscar M RuedaMRC Biostatistics, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0003-0008-4884

Funding

ANID Fondecyt de Iniciación 11251346Cancer Research UK (CRUK) Career Establishment Fellowship RCCCEA-May22∖100002UKRI MC_UU_00002/16
6 · The paper itself

Abstract

Multistate models were developed to model survival data where several midpoints and endpoints are of interest; and they have been particular successful in modeling dynamics of cancer. As in any statistical model, identification of influential observations is an essential task, as they can significantly affect the validity of inferred parameters and conclusions drawn from the data. The local influence approach is a set of methods designed to detect the effect of small perturbations of the model or data on the inference, allowing for deeper data analysis. In this paper, we derive local influence methods for multistate models and illustrate their use with a breast cancer dataset. In particular, we develop and implement local influence diagnostic techniques based on a suitable estimation equation. For simplicity, we restrict our consideration to the Multistate Proportional Hazards model, using different case-weight perturbation strategies.

Indexed as

Breast NeoplasmsModels, StatisticalComputer SimulationFemaleHumansLikelihood FunctionsProportional Hazards ModelsSurvival Analysisbreast cancercase‐weight perturbationcox‐partial likelihood functioninfluence diagnosticslikelihood inference

Identifiers

PMID42011007
PMCPMC13096765

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.