Evidence map›Paper›PMID 42011673›Full record

Observational studyCirculation. Cardiovascular interventions2026

Ultra-Low-Dose Noise-Free Technology to Reduce Radiation Exposure During Coronary Angiography.

Jinying Zhou, Qiyu Zhang, Hao Lu, Yizhe Wu, Li Shen, Jianying Ma, Rende Xu, Feng Zhang, Zhangwei Chen, Juying Qian and 2 more

Abstract readObservational StudyComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Circulation. Cardiovascular interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jinying ZhouDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0001-5597-4329
Qiyu ZhangDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.
Hao LuDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0002-0322-4400
Yizhe WuDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0002-8947-7969
Li ShenDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0002-6105-1202
Jianying MaDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0002-4344-6649
Rende XuDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0001-6313-4178
Feng ZhangDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0002-6170-3688
Zhangwei ChenDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0003-3223-5261
Juying QianDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0002-7512-3692
Chenguang LiDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.
Junbo GeDepartment of Cardiology (J.Z., Q.Z., H.L., Y.W., L.S., J.M., R.X., F.Z., Z.C., J.Q., C.L., J.G.), Zhongshan Hospital, Fudan University, China.ORCID 0000-0002-9360-7332

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous coronary intervention (PCI) is a cornerstone treatment for coronary artery disease. As procedural volumes continue to rise, the associated radiation risk from angiography systems has drawn increasing concern. Thus, we developed a novel ultra-low-dose Noise-Free technology to optimize angiography systems. This study aims to investigate whether it effectively reduces radiation exposure in real-world coronary interventions.

methodsA comparative study on a single-center, real-world, observational cohort. The primary end point was an intergroup comparison of procedural radiation exposure, including dose area product, air kerma, and dose rate, stratified by exposure mode (fluoroscopy or cine) and procedure type (diagnostic coronary angiography, single-vessel PCI, or chronic total occlusion PCI). The secondary end point included an expert semi-quantitative assessment and a quantitative contrast-to-noise ratio for image quality.

resultsA total of 380 procedures (102 coronary angiography, 78 single-vessel PCI, and 200 chronic total occlusion PCI) were performed in 380 patients using 4 different angiography systems. There was no significant difference in baseline patient characteristics, procedural time, or operator experience. In coronary angiography procedures, the ultra-low-dose technique demonstrated a total air kerma of 60.3 (38.5-74.1) mGy, total dose area product of 4.0 (2.9-5.2) Gy·cm

conclusionsThe Noise-Free technique reduced radiation exposure across cumulative and rate metrics while preserving diagnostic image quality, with the greatest reduction observed in complex cases. These findings support its clinical utility for lowering radiation risk.

Indexed as

Coronary AngiographyCoronary Artery DiseaseCoronary OcclusionPercutaneous Coronary InterventionRadiation DosageRadiation ExposureRadiography, InterventionalAgedCineangiographyFemaleFluoroscopyHumansMaleMiddle AgedPredictive Value of TestsRisk Assessmentcoronary angiographycoronary artery diseasefluoroscopyhumansradiation exposure

Identifiers

PMID42011673
PMCPMC13384380

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.