ArticleTranslational vision science & technology2026
Macular, Peripapillary, and Midperipheral Nonperfusion in Diabetic Subjects: A Wide-Field OCTA Quantification.
Article in Translational vision science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To identify and quantify the correlation between geometric perfusion deficit (GPD), a direct optical coherence tomography angiography (OCTA) metric of nonperfusion, in the macular, peripapillary, and midperipheral retina in diabetic patients, using widefield swept-source OCTA. Methods: Diabetic patients, with and without diabetic retinopathy (DR), underwent widefield swept-source OCTA imaging of the macula, peripapillary area, and four midperipheral retinal regions. GPD was calculated for each area, in macula both excluding (GPD) and including (GPDf) the foveal avascular zone. Correlations of GPD between regions were assessed. Results: We analyzed 197 diabetic eyes. A moderate-to-strong positive correlation was observed between macular and midperipheral GPD in both the superficial capillary plexus (SCP) and deep capillary plexus (DCP). The radial peripapillary capillary plexus (RPCP) also showed moderate correlations with midperipheral SCP and DCP. Subgroup analysis revealed that in both DR and no DR eyes, macular and midperipheral GPD and GPDf in SCP and DCP were significantly correlated. RPCP showed significant correlation with midperipheral DCP in DR eyes and with SCP in both groups. Conclusions: In diabetic patients, GPD in the macular SCP and DCP, as well as in the RPCP, correlates positively with perfusion deficits in the midperiphery. Translational Relevance: Optical coherence tomography angiography-based assessment of macular and peripapillary perfusion deficits enables noninvasive monitoring and may facilitate the early detection of peripheral vascular alterations in diabetic retinopathy, thus optimizing the diagnostic workflow for diabetic patients.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.