Evidence map›Paper›PMID 42013156›Full record

ArticlePloS one2026

Implementing the Lung Donor (LUNDON) acceptability score in U.S. donor management and transplant decision-making: A multi-aim, mixed-methods protocol.

Nikki E Rossetti, Samantha Morrison, Su-Hsin Chang, Yan Yan, Graham Jaensch-Frie, Charles R Liu, Nahom Y Seyoum, Meghna Katta, Arvind Kumar, Zhizhou Yang and 11 more

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Nikki E RossettiDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.ORCID https://orcid.org/0000-0001-5218-0902
Samantha MorrisonDepartment of Biostatistics & Bioinformatics, Duke University School of Medicine Durham, North Carolina, United States of America.
Su-Hsin ChangDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine St. Louis, Missouri, United States of America.
Yan YanDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine St. Louis, Missouri, United States of America.ORCID https://orcid.org/0000-0002-5917-1475
Graham Jaensch-FrieDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine St. Louis, Missouri, United States of America.
Charles R LiuDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Nahom Y SeyoumDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.ORCID https://orcid.org/0009-0007-3278-2798
Meghna KattaDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Arvind KumarDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Zhizhou YangDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Christian OnckenDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Christy HamiltonDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Nicholas SchroyUnited Network for Organ Sharing, Richmond, Virginia, United States of America.
Kyle StumbaughDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Gary MarklinMid-America Transplant, St. Louis, Missouri, United States of America.
Brendan HeidenDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Brendon CummiskeyUnited Network for Organ Sharing, Richmond, Virginia, United States of America.ORCID https://orcid.org/0000-0001-6505-1704
Sarah PeskoeDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine St. Louis, Missouri, United States of America.
Matthew HartwigDivision of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University School of Medicine Durham, North Carolina, United States of America.
Varun PuriDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Ana A BaumannDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine St. Louis, Missouri, United States of America.ORCID https://orcid.org/0000-0002-4523-0147

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite advances in transplantation science, a persistent shortage of donor lungs continues to limit access to life-saving lung transplants. The Lung Donor (LUNDON) Acceptability Score is a validated tool that predicts donor lung utilization and post-transplant recipient outcomes, but integration into practice remains limited. This study will evaluate determinants of LUNDON score adoption, its impact on clinical decision-making, and develop tools to support its implementation.

methodsThis is a multi-aim mixed-methods pre-implementation study that will be conducted across U.S. Organ Procurement Organizations (OPOs) and lung transplant centers. Aim 1 will identify barriers and facilitators of LUNDON score adoption through surveys (n = 242 participants) and interviews (n = 60 participants) of OPO and transplant providers. Aims 2 and 3 will evaluate the impact of the LUNDON score on donor management and organ acceptance using simulation-based experiments with OPO coordinators, OPO clinical leadership, transplant pulmonologists, and transplant surgeons (n = 120 total). Aim 4 will synthesize findings to develop and pilot implementation toolkits across three OPOs and three transplant centers. Two implementation frameworks [the Capability, Opportunity, and Motivation-Behavior (COM-B) model and the Theoretical Domains Framework (TDF)] will guide data collection and analysis, integrating quantitative and qualitative findings. EXPECTED IMPACT: Findings from this collaborative, nationally supported study involving partners from the United Network for Organ Sharing (UNOS) and the national lung transplant community will inform the development of toolkits to support LUNDON score adoption in clinical practice, with the goal of reducing variation in donor management and increasing donor lung utilization. Future studies will explore the effect of LUNDON score adoption on donor lung utilization and recipient outcomes.

Indexed as

Decision MakingLung TransplantationTissue and Organ ProcurementTissue DonorsHumansUnited States

Identifiers

PMID42013156
PMCPMC13098944

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.