ArticleBiogerontology2026
Gut microbiota as potential mediator linking dietary preferences and aging phenotypes.
Article in Biogerontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Aging is a complex process influenced by various factors, including gut microbiota and food likings. Focusing on gut and dietary health is a crucial strategy for promoting long-term health and active aging. This study investigates the reciprocal causal relationships between gut microbiota, food likings and aging using Mendelian Randomization (MR) approaches. We leveraged the summary statistics of gut microbiota (n = 5,959), food likings (n = 161,625), and three aging phenotypes including telomere length (n = 472,174), facial aging (n = 423,999), and frailty index (n = 175,226). We performed bidirectional MR analyses to explore the causal effects of gut microbiota and food likings on aging, and mediation analyses to discover potential mediating gut microbiota and food likings. We discovered numerous correlations between gut microbiota, food likings, and aging. Notably, we identified that Lachnospira rogosae and CAG-83 sp000435555 influenced the frailty index through diet fizzy drinks liking, while UBA2922 sp900313925 had an effect through F-wine liking. Our findings provide insights into these complex interactions and offer a basis for personalized dietary interventions to slow aging and improve health, potentially informing new strategies for preventing age-related diseases.
Indexed as
Identifiers
42014597What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.