Evidence map›Paper›PMID 42014628›Full record

ReviewNature reviews. Cancer2026

Advancing AI for multi-omics and clinical data integration in basic and translational cancer research.

Fei Liu, Stephan Beck, Lei Yang, Huiyan Luo, Kang Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fei LiuArtificial Intelligence Cross Disciplinary Research Institute and Faculty of medicine, Macau University of Science and Technology, Macau, China.ORCID http://orcid.org/0000-0003-1734-7214
Stephan BeckUniversity College London, Cancer Institute, London, UK.ORCID http://orcid.org/0000-0001-5290-2151
Lei YangDepartment of Orthopedics and Key Laboratory of Hepatosplenic Surgery of Ministry of Education, the First Affiliated Hospital, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin, China.
Huiyan LuoDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University, Guangzhou, China. luohy@sysucc.org.cn.
Kang ZhangArtificial Intelligence Cross Disciplinary Research Institute and Faculty of medicine, Macau University of Science and Technology, Macau, China. kang.zhang@gmail.com.ORCID http://orcid.org/0000-0002-4549-1697

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The extensive heterogeneity of cancer across biological scales necessitates a holistic approach beyond single-analyte methods. Integrating multi-omics data - from genomics to proteomics - with multimodal information, such as clinical records and medical imaging, offers a comprehensive, systems-level view of tumorigenesis. Artificial intelligence (AI) has emerged as the essential technology to decipher these complex, high-dimensional datasets, powering substantial advances in early diagnosis, precise patient stratification, prediction of therapeutic response and the elucidation of mechanisms of drug resistance. To translate these powerful predictive models into practice, explainable AI is critical for building clinical trust and generating novel, testable biological hypotheses. While challenges in data accessibility and model generalizability persist, the field is advancing toward patient-specific digital twins, promising to simulate individual disease trajectories and optimize treatments, thereby heralding a new era of precision oncology.

Indexed as

Artificial IntelligenceNeoplasmsTranslational Research, BiomedicalData AnalyticsGenomicsHumansMultiomicsPrecision MedicineProteomics

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.