Evidence map›Paper›PMID 42014991›Full record

ArticleBMC plant biology2026

Transcriptomic and metabolomic analysis reveals the role of Piriformospora indica in enhancing strawberry alkaline tolerance.

Wei Liu, Xue Gao, Luxiao Guo, Fei Gao, Songling Chen, Xinxin Song, Haoting Chen, Guoping Wang, Hua Guo, Qi Wang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wei LiuShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China.
Xue GaoShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China.
Luxiao GuoShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China.
Fei GaoShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China.
Songling ChenShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China.
Xinxin SongShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China.
Haoting ChenShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China.
Guoping WangNational-Local Joint Engineering Research Center for Horticultural Plants Virus-Free and Propagation Technology, Pomology Institute, Shanxi Agricultural University, Taiyuan, 030031, China.
Hua GuoNational-Local Joint Engineering Research Center for Horticultural Plants Virus-Free and Propagation Technology, Pomology Institute, Shanxi Agricultural University, Taiyuan, 030031, China.
Qi WangNational-Local Joint Engineering Research Center for Horticultural Plants Virus-Free and Propagation Technology, Pomology Institute, Shanxi Agricultural University, Taiyuan, 030031, China.
Yu ShiShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China.
Chunzhen ChengShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China.
Yi ZhangShanxi Key Laboratory of Germplasm Improvement and Utilization in Pomology, College of Horticulture, Shanxi Agricultural University, Jinzhong, 030801, China. harmony1228@163.com.
Xinping FanNational-Local Joint Engineering Research Center for Horticultural Plants Virus-Free and Propagation Technology, Pomology Institute, Shanxi Agricultural University, Taiyuan, 030031, China. xinping.fan@sxau.edu.cn.
Tianlai LiCollege of Horticulture, Shenyang Agricultural University, Shenyang, 110866, China. ltl@syau.edu.cn.

Funding

Earmarked fund for Modern Agro-industry Technology Research System of Shanxi Province 2023CYJSTX07-06Graduate Education Innovation Project in Shanxi Province 2022Y315Key Laboratory Open Fund Project of Shanxi Province PILAB2023150504Natural Science Research Project in Shanxi Province 202203021222145
6 · The paper itself

Abstract

Soil alkalinity severely limits the productivity of strawberry, a high-value horticultural crop. The root endophytic fungus Piriformospora indica enhances plant stress resilience, yet the systemic mechanisms underlying its promotion of alkaline tolerance remain poorly understood. This study employed an integrated transcriptomic and metabolomic approach to elucidate these mechanisms in strawberry under alkaline stress. Inoculation with P. indica significantly alleviated stress-induced growth inhibition, improving biomass accumulation and leaf development. Metabolomic profiling identified 1,352 DAMs, predominantly flavonoids and phenolic acids. Transcriptome analysis revealed 19,689 DEGs enriched in oxidoreductase activity, hormone signaling, and secondary metabolism. Multi-omics integration highlighted coordinated changes in the metabolism of pyruvate,alanine, aspartate and glutamate. P. indica maintained the balance of carbon and nitrogen allocation in strawberry under alkaline stress, an effect linked to the downregulation of argG, asnB, and GLT1. These findings suggest a putative systemic metabolic mechanism by which P. indica may enhance alkaline tolerance, potentially through rebalancing primary metabolism. This offers molecular insights into fungal-mediated stress adaptation in strawberry and supports its potential as a sustainable bio-inoculant for improving productivity in alkaline soils.

Indexed as

BasidiomycotaFragariaMetabolomeTranscriptomeGene Expression ProfilingHydrogen-Ion ConcentrationMetabolomicsMultiomicsStress, PhysiologicalAlkaline stressAmino acid metabolismMulti-omics analysisPiriformospora indicaStrawberry

Identifiers

PMID42014991
PMCPMC13235142

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.