Evidence mapPaperPMID 42015241Full record

ArticleBMC women's health2026

Relation between Helicobacter pylori infection and menopausal symptoms in diabetic women.

Nessren Mohamed Bahaa El Deen Mohamed, Noura Ali Ghazy Zidan, Sara Mohammed Foaud Hussein, Eman Hussein Soliman Altaweel, Neamat Abdelmageed Abdelmageed, Fatma Saffeyeldin Mohamed, Sally Abdelaziz Ahmed, Marwa Abdelaziz Abo Saree Yassien, Doaa Mohamed Salama Abdelmaqsoud, Sabah M Alkhawagah and 3 more

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Article in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

13 authors.

Nessren Mohamed Bahaa El Deen MohamedHepatogastroenterology and Infectious Diseases Department, Al-Azhar University, Cairo, Egypt. M_moez71@yahoo.com.
Noura Ali Ghazy ZidanHepatogastroenterology and Infectious Diseases Department, Al-Azhar University, Cairo, Egypt.
Sara Mohammed Foaud HusseinHepatogastroenterology and Infectious Diseases Department, Al-Azhar University, Cairo, Egypt.
Eman Hussein Soliman AltaweelHepatogastroenterology and Infectious Diseases Department, Al-Azhar University, Cairo, Egypt.
Neamat Abdelmageed AbdelmageedHepatogastroenterology and Infectious Diseases Department, Al-Azhar University, Cairo, Egypt.
Fatma Saffeyeldin MohamedHepatogastroenterology and Infectious Diseases Department, Al-Azhar University, Cairo, Egypt.
Sally Abdelaziz AhmedEndocrinology and Metabolism Department, Al-Azhar University, Cairo, Egypt.
Marwa Abdelaziz Abo Saree YassienEndocrinology and Metabolism Department, Al-Azhar University, Cairo, Egypt.
Doaa Mohamed Salama AbdelmaqsoudEndocrinology and Metabolism Department, Al-Azhar University, Cairo, Egypt.
Sabah M AlkhawagahMedical Microbiology and Immunology Department, Al-Azhar University, Cairo, Egypt.
Shymaa M ElattarClinical Pathology Department, Al-Azhar University, Cairo, Egypt.
Marwa M HassanInternal Medicine Department, Al-Azhar University, Cairo, Egypt.
Moshira Ali Ibrahim MohamedHepatogastroenterology and Infectious Diseases Department, Al-Azhar University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimMenopausal symptoms have marked negative impact on women’s physical and mental well-being and consumes substantial amount of health expenses. However, the relation between H. pylori infection and severity of menopausal symptoms is a scarcely discussed issue. The present cross-sectional study aims to explore the relation between H. pylori infection and severity of menopausal symptoms in diabetic women. SUBJECTS AND

methodsThe study included 150 postmenopausal diabetic women and 150 non-diabetic counterparts. H. pylori infection was assessed using a monoclonal enzyme immunoassay–based stool antigen test. Menopausal symptoms were evaluated using the Menopause Rating Scale (MRS).

resultsThe present study included consecutive 150 diabetic and 150 non-diabetic postmenopausal women. Diabetic women had significantly higher frequency of severe menopausal symptoms (31.3% versus 14.0%, p<0.001) and significantly higher frequency of positive H. pylori infection (56.0% versus 40.7%, p = 0.011). Multivariate binary logistic regression analysis identified significant association between BMI [OR (95% CI): 1.09 (1.01–1.18), p = 0.022], hypertension [OR (95% CI): 3.97 (1.66–9.49), p = 0.002], HbA1c % [OR (95% CI): 1.18 (1.02–1.36), p = 0.029] and positive H. pylori infection [OR (95% CI): 4.09 (1.52-11.0), p = 0.005] and severe menopausal symptoms.

conclusionsPostmenopausal diabetic women had higher frequency of H. pylori infection which may be related to more severe menopausal symptoms in this population.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 2Helicobacter InfectionsHelicobacter pyloriMenopausePostmenopauseBody Mass IndexCross-Sectional StudiesFemaleHumansMiddle AgedSeverity of Illness IndexDiabetes mellitusHelicobacter pyloriMenopausal symptoms

Identifiers

PMID42015241
PMCPMC13097901

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.