Evidence map›Paper›PMID 42015291›Full record

ArticleTrials2026

Treating suicidality remotely (TREASURE): study protocol for a remote randomized controlled trial comparing personalized cognitive behavioral therapy for suicide prevention with a guided self-help course in adolescents and adults.

Wilco Janssen, Saskia Mérelle, Renske Gilissen, Claudi Bockting

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06370104 (Treating Suicidality Remotely), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06370104 narecruitingnot on this map

Treating Suicidality Remotely: a Randomized Controlled Trial of Brief Cognitive Behavioral Therapy for Suicide Prevention Delivered Via Chat or Phone

TypeinterventionalSponsor113 Suicide PreventionRan2024 to 2028Enrolled364ConditionsSuicide AttemptArmsBrief Cognitive Behavioral Therapy for Suicide Prevention, Living under control
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wilco Janssen113 Suicide Prevention, Amsterdam University Medical Center, Amsterdam, The Netherlands. w.janssen@113.nl.ORCID http://orcid.org/0000-0003-1193-2957
Saskia Mérelle113 Suicide Prevention, Amsterdam, The Netherlands.
Renske Gilissen113 Suicide Prevention, Amsterdam, The Netherlands.
Claudi BocktingAmsterdam University Medical Center, Amsterdam, The Netherlands.

Funding

113 Suicide Prevention Fund 2023-03
6 · The paper itself

Abstract

backgroundPractical and psychological barriers make it difficult for people with Suicidal Thoughts and Behaviors (STBs) to obtain professional help. Remote interventions have the potential to overcome many of these barriers, but the remote interventions to date have produced small or short-lived effects and only reduced suicidal thoughts, not behaviors.

aimsThis study therefore aims to evaluate the effectiveness of remotely delivered brief cognitive behavioral therapy for suicide prevention (BCBT) in preventing suicide attempts in a fully remote randomized controlled trial, in which it will be compared to an online self-help course that has previously been found to be effective in reducing suicidal thoughts.

methodsA randomized controlled trial will be conducted in which 364 participants aged 16 years and older will be recruited through the website of the Dutch suicide prevention helpline and randomized at a ratio of 1:1 to one of two interventions, both delivered via chat or phone. Participants in the experimental condition will receive BCBT. This intervention consists of approximately 12 sessions in which a narrative assessment of a recent suicidal crisis is used to create a personalized treatment plan out of several modules, such as cognitive restructuring, mindfulness and means restriction. Participants in the control group will receive a semiguided self-help course, which includes 6 lessons and 6 feedback sessions with a therapist, focusing predominantly on psychoeducation and cognitive restructuring. The primary outcome of the study is the number of suicide attempts, measured with the Columbia Suicide Severity Rating Scale (C-SSRS). Secondary outcomes are the self-reported severity of suicidal ideation, treatment satisfaction, adverse effects, and quality of life. All outcomes will be assessed at baseline, immediately after treatment and at 18-month follow-up. DISCUSSION: If remote BCBT proves effective, the findings of this study will add to the evidence base of BCBT as one of few replicated psychological interventions that can reduce suicide attempts and pave the way for the wider dissemination of this remote intervention.

trial registrationClinicaltrials.gov NCT06370104. Registered on April 8, 2024.

Indexed as

Adolescent BehaviorCognitive Behavioral TherapyMental Health TeletherapySelf CareSuicidal IdeationSuicide PreventionAdolescentAdultFemaleHumansNetherlandsRandomized Controlled Trials as TopicSuicide, AttemptedTime FactorsTreatment OutcomeYoung AdultAdolescentsAdultsAttemptsCBTe-healthIdeationSelf-helpSuicideTelehealthYoung adults

Identifiers

PMID42015291
PMCPMC13231569

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.