Evidence map›Paper›PMID 42015627›Full record

SynthesisCanadian journal of gastroenterology & hepatology2026

Effects of Internet-Based Lifestyle Interventions on Nonalcoholic Fatty Liver Disease: A Meta-Analysis of Randomized Controlled Trials.

Chengjie Wang, Yilong Song, Jingjing Wu, Hua Mei

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Canadian journal of gastroenterology & hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chengjie WangShanghai University of Traditional Chinese Medicine, Shanghai, 201203, China, shutcm.edu.cn.ORCID 0009-0002-6920-6376
Yilong SongShanghai University of Traditional Chinese Medicine, Shanghai, 201203, China, shutcm.edu.cn.ORCID 0009-0004-3475-7068
Jingjing WuShanghai University of Traditional Chinese Medicine, Shanghai, 201203, China, shutcm.edu.cn.ORCID 0009-0008-9875-4172
Hua MeiShanghai University of Medicine and Health Sciences, Shanghai, 201318, China, sumhs.edu.cn.ORCID 0009-0007-8568-8199

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the efficacy of internet-based interventions in improving clinical outcomes among patients with nonalcoholic fatty liver disease (NAFLD) and to synthesize evidence for future research directions.

methodsA comprehensive search of nine electronic databases (CNKI, Wanfang, VIP, CBM, PubMed, Web of Science, Cochrane Library, Embase, and CINAHL) was conducted from inception to September 23, 2024, to identify randomized controlled trials (RCTs) assessing internet-based lifestyle interventions in NAFLD patients. Two independent researchers screened studies, extracted data, and evaluated methodological quality. Meta-analyses were performed using RevMan 5.3.5 software.

resultsTen RCTs involving 714 participants were included. Compared to the control group, the intervention groups showed significant reductions in BMI, ALT and AST. Weight loss trended toward reduction but was not statistically significant, though subgroup analysis showed significant weight loss in interventions lasting > 3 months.

conclusionInternet-based interventions significantly improve BMI and liver enzymes in NAFLD patients, with prolonged interventions (> 3 months) enhancing weight loss. Digital platforms show promise for enhancing self-management, though standardized long-term trials are needed to optimize efficacy.

Indexed as

Internet-Based InterventionLife StyleNon-alcoholic Fatty Liver DiseaseBody Mass IndexHumansRandomized Controlled Trials as TopicWeight Lossinternet-based interventionlifestylemeta-analysisNAFLD

Identifiers

PMID42015627
PMCPMC13580839

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.