ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2026
[Association between early fluid overload and critical complications in extremely low birth weight infants].
Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo explore the relationship between fluid balance during the first 14 postnatal days and critical clinical complications in extremely low birth weight infants (ELBWIs), with the aim of reducing the impact of fluid overload on adverse outcomes.
methodsClinical data of 226 ELBWIs admitted to the neonatal intensive care unit of the Affiliated Obstetrics and Gynecology Hospital of Nanjing Medical University from January 2019 to December 2024 were retrospectively analyzed. Infants who developed severe bronchopulmonary dysplasia (sBPD) or died were classified as the critical complication group (
resultsUnivariate analysis showed that fluid balance on postnatal days 3, 7, 10, and 14, as well as weight loss <3% within the first 3 days and <6% within the first 7 days, was significantly associated with the occurrence of critical complications (all
conclusionsIn ELBWIs, early fluid overload may be associated with an increased risk of sBPD or death, and moderate fluid restriction may help improve prognosis; prospective studies are required for further validation.
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