ArticleLaryngoscope investigative otolaryngology2026
Association Between Reflux Symptom Severity and Sleep Quality in Patients With Laryngopharyngeal Reflux: A Cross-Sectional Observational Study.
Article in Laryngoscope investigative otolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to investigate the relationship between reflux symptom severity and sleep quality in patients diagnosed with laryngopharyngeal reflux (LPR). Methods: This cross-sectional observational study included 153 patients aged 20-75 years who were diagnosed with LPR at our clinic. Reflux symptom severity was measured using the Reflux Symptom Index (RSI), and sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI). Demographic characteristics, RSI scores, and PSQI total and subcomponent scores were analyzed. Correlations between the RSI and PSQI total and subcomponent scores were evaluated using Spearman's correlation test. Additionally, a multiple linear regression analysis was performed to evaluate the independent association between RSI and PSQI scores while adjusting for age. Results: The study included 153 patients (84 females, 69 males) with a mean age of 49.1 ± 12.8 years. The mean RSI total score was 20.7 ± 4.6, and the mean PSQI total score was 6.8 ± 1.5. RSI and PSQI were weakly but significantly correlated ( Conclusion: LPR symptom severity was significantly associated with impaired sleep quality, particularly in the domains of sleep efficiency and daytime functioning. Routine assessment of sleep quality in patients with LPR may enhance the treatment outcomes and patient satisfaction.
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