Evidence mapPaperPMID 42016369Full record

ArticleInfection and drug resistance2026

Clinical Impact of Polymicrobial Interactions in Human-Metapneumovirus-Infected Children: A Targeted Next-Generation Sequencing Based Retrospective Study.

Mingshan Huang, Junli Ji, Suhong Huang, Ling Liang, Qiuyu Tang, Feng Cheng

Abstract read
In one paragraph

Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mingshan Huang *School of Medical Technology and Engineering, Fujian Health College, Fuzhou, 350000, People's Republic of China.
Junli Ji *Department of Clinical Laboratory, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350000, People's Republic of China.
Suhong HuangDepartment of Clinical Laboratory, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350000, People's Republic of China.
Ling LiangSchool of Medical Technology and Engineering, Fujian Health College, Fuzhou, 350000, People's Republic of China.
Qiuyu TangDepartment of PICU, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350000, People's Republic of China.ORCID 0000-0002-2869-9007
Feng ChengDepartment of Clinical Laboratory, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Patients and Methods: This retrospective study enrolled 526 hospitalized children with Results: The median age of the inpatients was 36 months, and 15.6% required ICU admission. The overall prevalence of co-detection among the cohort was 100% since we identified at least one pathogen in the existing results from tNGS. The co-colonization or co-infection pathogen spectrum demonstrated significant age specificity, temporal dynamics, and sample type dependency. Multivariable analysis identified several pathogens independently associated with severe outcomes. Specifically, opportunistic and atypical pathogens (such as Conclusion: Despite limitations including a single-center retrospective design and the absence of an hMPV-negative control group, the co-colonization or co-infection pathogen spectrum in children with

Indexed as

bacterial-viral interactionsco-colonizationsco-infectionhuman metapneumoviruspediatricstargeted NGS diagnostics

Identifiers

PMID42016369
PMCPMC13094763

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.