Evidence map›Paper›PMID 42016723›Full record

ArticleContemporary clinical trials communications2026

Addressing financial and health-related social needs among patients with cancer: Study protocol for CAN-ASSIST pilot clinical trial.

Maedeh Sharifian, Victoria Nguyen, Aarushi Madan, Omar Gutierrez, Mahnur Bharucha, Jeremy Harris, Michael A Hoyt, Joel Milam, Wen-Pin Chen, Argyrios Ziogas and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in Contemporary clinical trials communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06430840 (Addressing Financial and Social Needs Among Patients With Cancer), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06430840 naactive not recruitingnot on this map

Addressing Financial and Social Needs Among Patients With Cancer

TypeinterventionalSponsorUniversity of California, IrvineRan2024 to 2026Enrolled91ConditionsCancer, Financial HardshipArmsCostCOM (Cost Communication, Financial navigation and counseling), Provision of local and national resources to address financial and social needs, Financial Education, Usual care, Screening for financial and social needs
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maedeh SharifianDepartment of Radiological Sciences, University of California Irvine, CA, USA.
Victoria NguyenDepartment of Radiological Sciences, University of California Irvine, CA, USA.
Aarushi MadanDepartment of Radiological Sciences, University of California Irvine, CA, USA.
Omar GutierrezDepartment of Radiological Sciences, University of California Irvine, CA, USA.
Mahnur BharuchaDepartment of Radiological Sciences, University of California Irvine, CA, USA.
Jeremy HarrisDepartment of Radiation Oncology, University of California Irvine, CA, USA.
Michael A HoytDepartment of Population Health and Disease Prevention, University of California Irvine, Irvine, CA, USA.
Joel MilamDepartment of Epidemiology and Biostatistics, University of California Irvine, Irvine, CA, USA.
Wen-Pin ChenChao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA.
Argyrios ZiogasChao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA.
Gelareh SadighDepartment of Radiological Sciences, University of California Irvine, CA, USA.

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
NCI NIH HHS P30 CA062203
6 · The paper itself

Abstract

Background: Financial hardship and health-related social needs (HRSNs) are prevalent among cancer patients and contribute to disparities in outcomes. Addressing these issues can reduce harm, yet routine screening and intervention remains underutilized. Navigator-led interventions such as combining out-of-pocket cost (OOPC) communication and financial navigation (CostCOM) have shown promise, but face implementation barriers due to navigator shortages. It is unclear whether financial education and resource access alone (FinEd), without navigator support, can meet patients' needs. Method: We propose a three-arm pilot randomized controlled trial comparing FinEd, enhanced usual care (EUC) and CostCOM in 90 newly diagnosed cancer patients undergoing systemic or radiation therapy who screen positive for financial hardship or HRSNs. FinEd includes (1) a list of local/national resources for financial and HRSNs support, and (2) educational materials on health insurance, delivered via mail and a one-time phone/video session with a study coordinator. CostCOM includes (1) systemic therapy OOPC estimates, (2) financial navigation to identify assistance programs, and (3) financial counseling, delivered over two phone/video sessions by a financial navigator. EUC includes study-specific identification of financial hardship and HRSNs. Our goals are to investigate preliminary efficacy of the three arms within six months post-randomization on cost-related care non-adherence (primary outcome), treatment completion, missed appointments, financial worry, material hardship, insurance literacy, quality of life, and sleep quality. We will evaluate patient experience with FinEd using qualitative interviews. Conclusion: This study will support feasibility for a larger trial, and provide initial efficacy estimates comparing FinEd vs. EUC vs. CostCOM in improving cancer outcomes. Trial registration: Clinicaltrials.gov NCT06430840; registered 5/24/2024; https://clinicaltrials.gov/study/NCT06430840?cond=NCT06430840&rank=1.

Indexed as

CancerCost communicationFinancial educationFinancial hardshipFinancial navigationHealth-related social needs

Identifiers

PMID42016723
PMCPMC13092577

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.