ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Identifying predictors of tracheostomy or death in preterm infants with grade 3 BPD.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
objectiveTo identify novel risk factors associated with tracheostomy in preterm infants with Grade 3 bronchopulmonary dysplasia (BPD). STUDY
designSingle-center retrospective cohort of infants with Grade 3 BPD (mechanical ventilation at 36 weeks' postmenstrual age) from 2019 to 2025. Data included extubation attempts, corticosteroid and neuromuscular blockade use, mean airway pressure (MAP) and respiratory severity scores (RSS) at 36 and 40 weeks. Infants who received tracheostomy or died were compared to those successfully extubated.
resultsOf 60 infants, 37% underwent tracheostomy. Patients requiring tracheostomy had higher MAP (17 vs. 12 cm H₂O) and RSS (6 vs. 4) at 40 weeks, with no difference at 36 weeks. Patients requiring tracheostomy experienced more steroid courses, need for neuromuscular blockade, and failed extubations.
conclusionsNumber of steroid courses, neuromuscular blockade, and ventilator settings at 40 weeks were associated with tracheostomy placement. These variables could inform future data collection strategies for infants with severe BPD.
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