ArticleFrontiers in pharmacology2026
Dual mechanisms of a purified root extract of
Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Hyperuricemia (HUA), characterized by persistently elevated serum uric acid (UA), represents a growing global public-health concern. Current urate-lowering medications are often associated with hepatotoxicity and nephrotoxicity, highlighting the urgent need for safer, food-derived alternatives. Methods: A macroporous resin-purified fraction (PLE-2) from Results: Discussion: PLE-2 demonstrates potent dual action on UA synthesis and excretion with notable nephroprotective effects, positioning the purified fraction as a promising functional food metabolite for preventing and ameliorating HUA.
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