ArticleHealth science reports2026
Associations Between the Severity of Obstructive Sleep Apnea and Arterial Stiffness Estimated by Pulse Wave Velocity Assessment: A Cross-Sectional Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Background and Aims: Obstructive sleep apnea (OSA) is a prevalent sleep disorder linked to cardiovascular diseases and is highly prevalent, especially in the elderly population. This study aimed to investigate the association between OSA severity and arterial stiffness, as measured by pulse wave velocity (PWV), in patients with moderate to severe OSA. Methods: This cross-sectional study included 60 adults with moderate-to-severe OSA, confirmed by polysomnography (PSG). Arterial stiffness was measured by brachial artery oscillometry. Polysomnographic parameters, including the apnea-hypopnea index (AHI), minimum oxygen saturation (SpO2), and sleep efficiency, were analyzed to determine their correlation with PWV. Correlations between PWV and PSG parameters were performed using Spearman's correlation coefficient. Additionally, multivariate regression analysis was conducted to adjust for confounders, including age, sex, BMI, hypertension, diabetes, and medication use. Results: The mean age of participants was 62.07 ± 8.83 years, with 55% being male. A significant positive correlation was found between PWV and AHI ( Conclusion: The study confirms a significant initial association between the severity of OSA, as indicated by AHI and minimum SpO
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