ArticleTransplantation direct2026
Effect of Donor-recipient Size on Graft Growth in Pediatric Donor-to-pediatric Recipient Kidney Transplantation.
Article in Transplantation direct, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Kidney transplantation is the optimal treatment for pediatric end-stage kidney disease, yet donor shortages have driven the use of pediatric donor kidneys through pediatric donor-to-pediatric recipient (PTP) kidney transplantation. This study aimed to investigate the effect of donor-recipient size on graft growth in PTP kidney transplantation. Methods: This retrospective cohort study included kidney transplant recipients who underwent regular follow-ups between January 2016 and December 2023 at the Children's Hospital of Fudan University. All donors were deceased and aged <18 y. Dynamic clinical data were obtained from medical records spanning the pretransplant to posttransplant period. Results: A total of 136 patients were enrolled, 93 of whom had an initial transplant kidney length. Cumulative average growth of kidney length was 5.5 mm at 1 mo, 9.9 mm at 3 mo, 15.3 mm at 6 mo, 22.3 mm at 1 y, 31.5 mm at 3 y, and 39.5 mm at 5 y posttransplant. The corresponding growth rates were 8.3%, 15.1%, 22.3%, 30.6%, 41.3%, and 53.4%. Kidney growth rates were negatively correlated with the donor-recipient body weight ratio at 3 mo, 6 mo, and 1 y posttransplant ( Conclusions: Grafts showed stable growth patterns and favorable short-term follow-up outcomes. Additionally, PTP kidney transplantation demonstrated both clinical value and practical utility.
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Registered trials
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