Evidence map›Paper›PMID 42026076›Full record

ArticleNature communications2026

CAR-CD34 (+) hematopoietic stem/progenitor cells produced in vivo protect against thoracic aortic aneurysm and dissection.

Kaiwen Zhao, Yuzhen He, Renqi Yao, Shuangshuang Li, Lingxu Kong, Jinzhu Niu, Zan Zeng, Pengcheng Du, Hongqiao Zhu, Rong Zhao and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kaiwen Zhao *Department of Thoracic Surgery, the Seventh Medical Center of the Chinese PLA General Hospital, Beijing, China.ORCID http://orcid.org/0009-0008-4144-5627
Yuzhen He *Department of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.
Renqi Yao *Department of General Surgery, the First Medical Center of the Chinese PLA General Hospital, Beijing, China.
Shuangshuang LiDepartment of Vascular Surgery, the Third Affiliated Hospital, Naval Medical University, Shanghai, China.
Lingxu KongDepartment of Vascular Surgery, the Third Affiliated Hospital, Naval Medical University, Shanghai, China.ORCID http://orcid.org/0009-0007-4614-6872
Jinzhu NiuDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID http://orcid.org/0009-0009-5415-1406
Zan ZengDepartment of Vascular Surgery, the Third Affiliated Hospital, Naval Medical University, Shanghai, China.ORCID http://orcid.org/0000-0002-4017-4828
Pengcheng DuDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID http://orcid.org/0000-0001-5180-5851
Hongqiao ZhuDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.
Rong ZhaoDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID http://orcid.org/0000-0002-9048-5739
Taiping LiangDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.ORCID http://orcid.org/0009-0006-0797-7617
Zaiping JingDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.
Jian ZhouDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, China. zhoujian1_3@163.com.ORCID http://orcid.org/0009-0001-8217-1561

Funding

National Natural Science Foundation of China (National Science Foundation of China) 8227021836National Natural Science Foundation of China (National Science Foundation of China) 82570560,
6 · The paper itself

Abstract

Thoracic aortic aneurysm and dissection is one of the most devastating cardiovascular diseases, with limited medical intervention options. This study aims to develop chimeric antigen receptor-engineered CD34

Indexed as

Antigens, CD34Aortic Aneurysm, ThoracicAortic DissectionHematopoietic Stem CellsHematopoietic Stem Cell TransplantationReceptors, Chimeric AntigenAnimalsCell AdhesionCell DifferentiationCell MovementCell ProliferationDisease Models, AnimalDissection, Thoracic AortaEndothelial CellsHumansMaleAntigens, CD34Receptors, Chimeric AntigenVascular Cell Adhesion Molecule-1Vascular Endothelial Growth Factor A

Identifiers

PMID42026076
PMCPMC13315708

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.