Evidence mapPaperPMID 42027675Full record

ReviewInternational journal of cardiology. Cardiovascular risk and prevention2026

Cardiovascular disease burden in children with obesity: A narrative review.

Sulafa K M Ali, Bashir H Elnaem, Mohamed A Abdullah, Emily M D'Agostino

Abstract readReview
In one paragraph

Review in International journal of cardiology. Cardiovascular risk and prevention, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sulafa K M AliPediatric Cardiology, University of Sharjah, United Arab Emirates.
Bashir H ElnaemPediatric Endocrinologist, Al Qassimi Women's & Children's Hospital, United Arab Emirates.
Mohamed A AbdullahPediatric Endocrinology, University of Khartoum, Sudan.
Emily M D'AgostinoDepartment of Orthopedic Surgery, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood obesity is increasing alarmingly and cardiovascular disease (CVD), a major complication of obesity, is documented to begin early during childhood and has detectable, preventable stages. The current guidelines for mitigating CVD prevalence do not incorporate tests for diagnosis of subclinical atherosclerosis. A literature search under the key words "obesity, children, cardiovascular, subclinical atherosclerosis, vascular health, cardiometabolic" was conducted to cover the period from 2010 to 2025 in PubMed and the Cochrane Database of Systematic Reviews for articles published up to October 1, 2025, using combinations of terms such as "child", "adolescent", "obesity", "epidemiology", "etiology", "complications", "cardiovascular", "treatment", "atherosclerosis", "prevention", "endothelial function", "pharmacotherapy", and "BMI". Data about the diagnosis, and management of obesity and its CVD complications were summarized in this paper. Atherosclerosis is documented to have detectable subclinical, potentially reversible stages during childhood. The current guidelines for risk stratification do not account for the cumulative vascular burden of obesity leaving early subclinical stages undetected. While tools such as carotid intima-media thickness and carotid-femoral pulse wave velocity show clear associations with obesity and cardiometabolic risk, there is still lack of consensus on their use in routine care. More research is needed to identify tools that can be incorporated into clinical guidelines for diagnosis of subclinical CVD in children with obesity.

Indexed as

CardiovascularChildrenObesity

Identifiers

PMID42027675
PMCPMC13101726

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.