Evidence map›Paper›PMID 42027807›Full record

ArticleGenes & diseases2026

Sex-dependent impact of

Fangzheng Chen, Yufei Duan, Mengze Wang, Zhaolin Liu, Jiayin Zhao, Guangchun Fan, Yongtao He, Hongtian Dong, Xiaoshuang Zhang, Rong Fang and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes & diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Fangzheng ChenDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Yufei DuanDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Mengze WangDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Zhaolin LiuDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Jiayin ZhaoDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Guangchun FanDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Yongtao HeDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Hongtian DongDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Xiaoshuang ZhangDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Rong FangDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Yunhe ZhangDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Xin YanDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Chenye ShenDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Xiwen TangDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Yuanyuan MaDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Mei YuDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Renyuan ZhouDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.
Jian FeiSchool of Life Science and Technology, Tongji University, Shanghai 200092, China.
Fang HuangDepartment of Translational Neuroscience, Department of Urology, Jing'an District Centre Hospital of Shanghai, National Key Laboratory of Brain Function and Diseases and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a prevalent neurodegenerative disorder accompanied by neuroinflammation. Many studies have demonstrated that interleukin-6 (IL-6) exhibits both anti-inflammatory and pro-inflammatory effects in the central nervous system, yet its role in PD remains controversial. In this study,

Indexed as

IL-6MPTPNeuroinflammationParkinson’s diseaserIL-6

Identifiers

PMID42027807
PMCPMC13099946

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.