Evidence map›Paper›PMID 42028916›Full record

ArticleEmerging microbes & infections2026

Treatment with low-dose bicistronic immunotherapy mitigates parasite persistence and improves serological and cardiac outcomes in adult mice infected with

Subhadip Choudhuri, Allison Wyrick, Nandadeva Lokugamage, Siddhartha De, Upendra Marathi, Nisha Jain Garg

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Subhadip ChoudhuriDepartment of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, TX, USA.
Allison WyrickDepartment of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, TX, USA.
Nandadeva LokugamageDepartment of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, TX, USA.
Siddhartha De7 Hills Pharma Inc, Houston, TX, USA.
Upendra Marathi7 Hills Pharma Inc, Houston, TX, USA.
Nisha Jain GargDepartment of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, TX, USA.

Funding

Integrin activator-adjuvanted DNA vaccine against Trypanosoma cruzi infectionR44AI172437 · NIAID · 7 HILLS PHARMA, LLC · PI DE, SIDDHARTHA, GARG, NISHA JAIN · 2022 to 2024
$3.0M
NIAID NIH HHS R44 AI172437
6 · The paper itself

Abstract

Chagas disease (CD), caused by

Indexed as

Chagas DiseaseImmunotherapyNitroimidazolesTrypanocidal AgentsTrypanosoma cruziAnimalsChagas CardiomyopathyDisease Models, AnimalFemaleHeartMaleMiceMice, Inbred C57BLbenzonidazoleNitroimidazolesTrypanocidal AgentscardiomyopathyChagas diseaseimmunotherapyleft ventricular functionTrypanosoma cruzi

Identifiers

PMID42028916
PMCPMC13162553

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.