Evidence mapPaperPMID 42032092Full record

Reviewnpj biomedical innovations2025

Exosomes: bridge metabolic regulation in cardiac repair.

Lewen Mao, Zhang Yue, Dashuai Zhu, Chao Lu, Ke Cheng

Abstract readReview
In one paragraph

Review in npj biomedical innovations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lewen MaoDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Zhang YueDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Dashuai ZhuDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Chao LuDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Ke ChengDepartment of Biomedical Engineering, Columbia University, New York, NY, USA. ke.cheng@columbia.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac repair following cardiovascular diseases relies heavily on coordinated metabolism across different cells. Exosomes, or small extracellular vesicles secreted by cells, have emerged as pivotal regulators of the metabolic process. This review offers an introductory exploration of the intricate role played by exosomes in cardiac repair and regeneration. Specific metabolism regulation, including metabolism and immune response alterations, is emphasized and analyzed. Additionally, we explore some innovative engineering strategies for improving the therapeutic potential of exosomes in this field. This article aims to provide an integrated framework of comprehension toward exosomes and metabolism in cardiac repair and pave the way for novel therapy designs for cardiovascular diseases by outlining future directions for clinical translation.

Identifiers

PMID42032092
PMCPMC13055089

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.