Evidence map›Paper›PMID 42034331›Full record

ArticleChest2026

The Association of Menopause With Lung Function in Women With and Without HIV.

Rebecca A Abelman, Fan Xia, M Bradley Drummond, Mirjam-Colette Kempf, Maria L Alcaide, Lauren F Collins, Amanda Blair Spence, Brandilyn A Peters, Deborah Gustafson, Ken M Kunisaki and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chest, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rebecca A AbelmanDepartments of Medicine, and Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA. Electronic address: Rebecca.abelman@ucsf.edu.
Fan XiaDepartments of Medicine, and Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA.
M Bradley DrummondDepartment of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC.
Mirjam-Colette KempfSchool of Nursing, Public Health and Medicine, University of Alabama at Birmingham, Birmingham, AL.
Maria L AlcaideDepartment of Medicine, Miller School of Medicine, Miami, FL.
Lauren F CollinsDepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA.
Amanda Blair SpenceDepartment of Medicine, Georgetown University Medical Center, Washington, DC.
Brandilyn A PetersDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx.
Deborah GustafsonDepartment of Neurology, State University of New York Downstate Health Sciences University, Brooklyn, NY.
Ken M KunisakiDepartment of Research, Boise Veterans Affairs Medical Center, Boise, ID.
Richard J WangDepartment of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI.
Phyllis C TienDepartments of Medicine, and Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA.
Laurence HuangDepartments of Medicine, and Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA.

Funding

The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in WomenK23HL178394 · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2025 to 2025
$199k
NHLBI NIH HHS K23 HL178394
6 · The paper itself

Abstract

backgroundMenopause accelerates lung function decline in women without HIV, but whether menopause modifies lung function in women with HIV (WWH) is unknown. RESEARCH QUESTION: Is menopause associated with lung function in WWH and women at risk for HIV? STUDY DESIGN AND

methodsPulmonary function tests (spirometry: n = 1,116; diffusing capacity for carbon monoxide [Dlco]: n = 615) collected from 2018 to 2019 in 1,206 participants from the Women's Interagency HIV Study were included. In this cross-sectional analysis, women were categorized into groups defined by age (41-50 and 51-60 years of age) and by menopausal phase as determined by anti-Müllerian hormone, a biomarker of ovarian reserve. Linear regression models determined the differences in mean FEV

resultsOverall, 71% were WWH, 65% were Black, and the median age was 52 years. Of the participants, 36% and 31% reported current and former smoking, respectively. A total of 30% were premenopausal/early perimenopausal, 40% were late perimenopausal, and 30% were postmenopausal. There was no statistically significant association of HIV with FEV

interpretationOur results show that menopausal phase is associated with lung function in WWH and women without HIV, even after accounting for age. Further research is needed to understand how estrogen depletion alters lung function.

Indexed as

COPDHIVmenopausewomen

Identifiers

PMID42034331
PMCPMC13160286

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.