Evidence map›Paper›PMID 42035989›Full record

ArticleJournal of sleep research2026

Enhanced Risk Stratification of Atrial Fibrillation Detected After Ischemic Stroke and TIA: The Role of Apnoea-Hypopnoea Index and Hypoxic Burden-A Study From the Bern Sleep-Stroke Registry.

Xiaoli Yang, Julian Lippert, Irina Filchenko, Christian M Horvath, Sebastien Baillieul, Corrado Bernasconi, Stefan A Bauer-Gambelli, Anne-Kathrin Brill, David J Seiffge, Elias Auer and 5 more

Abstract read
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In one paragraph

Article in Journal of sleep research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiaoli YangDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-7873-9169
Julian LippertDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Irina FilchenkoDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-9486-1017
Christian M HorvathDepartment of Pulmonary Medicine, Allergology and Clinical Immunology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Sebastien BaillieulHP2 Laboratory, INSERM U1300, Grenoble Alpes University Hospital, Grenoble Alpes University, Grenoble, France.
Corrado BernasconiDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Stefan A Bauer-GambelliDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Anne-Kathrin BrillInterdisciplinary Sleep-Wake-Epilepsy-Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
David J SeiffgeDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Elias AuerDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Tobias ReichlinDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Urs FischerDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Marcel ArnoldDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Markus H SchmidtDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Claudio L A BassettiUniversity of Bern and Department of Neurology, Inselspital, Bern University Hospital, Bern, Switzerland.

Funding

Bern Medtech Collaboration Call 2024 BMCC_2405China Scholarship Council 202108170016Swiss Heart Foundation FF19030Swiss National Science Foundation SNF-320030_149752
6 · The paper itself

Abstract

Sleep-disordered breathing is an independent risk factor for stroke and atrial fibrillation. Accurate assessment of atrial fibrillation in stroke patients with sleep-disordered breathing is crucial for secondary prevention. This study aimed to determine whether combining apnoea-hypopnoea index and hypoxic burden improves risk stratification for atrial fibrillation detected after ischemic stroke. About 911 patients with ischemic stroke underwent respiratory polygraphy within 3 days after an event. Hypoxic burden was defined as the cumulative area under the oxygen desaturation curve of respiratory events. Atrial fibrillation was monitored with up to three 7-day electrocardiogram recordings within 6 months. Patients were stratified by apnoea-hypopnoea index (≥ 15 vs. < 15 events/h) and by hypoxic burden (above vs. below the median, 35% min h

Indexed as

Atrial FibrillationHypoxiaIschemic Attack, TransientIschemic StrokeSleep Apnea SyndromesStrokeAgedElectrocardiographyFemaleHumansMaleMiddle AgedPolysomnographyRegistriesRisk AssessmentRisk Factorsacute ischemic strokecardiac arrhythmiassleep apnoea syndromes

Identifiers

PMID42035989
PMCPMC13357886

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.