ReviewAdvances in experimental medicine and biology2026
Advances in the Clinical Application of Neurostimulation in Major Depression.
Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For many individuals diagnosed with major depression, standard treatments such as antidepressant medication or psychotherapy do not lead to the desired symptom relief. Over the last several decades, a variety of neurostimulation techniques have evolved as promising treatments for patients with treatment-resistant depression. Here, we review clinical applications and significant advancements of the most common neurostimulation modalities, including electroconvulsive therapy, magnetic seizure therapy, transcranial magnetic stimulation, transcranial direct current stimulation, transcranial alternating current stimulation, vagus nerve stimulation, deep brain stimulation, and focused ultrasound. Modalities are examined in terms of their current use for treating major depression, therapeutic efficacy, assumed underlying mechanisms, safety profile, and current challenges. Furthermore, recent developments and ongoing research aimed at improving the personalization, safety, and accessibility of neurostimulation treatments are discussed.
Indexed as
Identifiers
42036585What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.