Evidence map›Paper›PMID 42037323›Full record

ReviewSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi2026

[Discussion on the design approach and results evaluation key points of repeated exposure systemic toxicity tests for absorbable medical devices].

Chunguang Fan, Qingyu Li, Guangyu Sun, Li Hou, Jing Zhang, Chenghu Liu

Abstract readReviewEnglish Abstract
In one paragraph

Review in Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chunguang FanShandong Institute for Medical Device and Pharmaceutical Packaging Inspection, Jinan 250101, P. R. China.
Qingyu LiShandong Institute for Medical Device and Pharmaceutical Packaging Inspection, Jinan 250101, P. R. China.
Guangyu SunShandong Institute for Medical Device and Pharmaceutical Packaging Inspection, Jinan 250101, P. R. China.
Li HouShandong Institute for Medical Device and Pharmaceutical Packaging Inspection, Jinan 250101, P. R. China.
Jing ZhangShandong Institute for Medical Device and Pharmaceutical Packaging Inspection, Jinan 250101, P. R. China.
Chenghu LiuShandong Institute for Medical Device and Pharmaceutical Packaging Inspection, Jinan 250101, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compared to non-absorbable medical devices, the design and evaluation of repeated exposure systemic toxicity tests for absorbable medical devices present unique challenges. This article discusses the special considerations for conducting such tests on absorbable medical devices. Based on regulatory documentation, scientific literature and practical experience, and focusing on the degradation and metabolic characteristics of absorbable medical devices, the analysis summarizes personalized test design strategies from key aspects such as test duration and data collection points, exposure routes, dose design, sample preparation, and pathological examination. This article proposes the following points: ① the test duration should cover the

Indexed as

Absorbable ImplantsBiocompatible MaterialsEquipment and SuppliesToxicity TestsAnimalsHumansMaterials TestingBiocompatible MaterialsAbsorbable medical devicesDegradation and metabolismRepeated systemic toxicity testTest designToxicological evaluation

Identifiers

PMID42037323
PMCPMC13112224

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.