Evidence map›Paper›PMID 42037524›Full record

ArticleChemistry & biodiversity2026

Exploring the Nutraceutical Potential of Extra Virgin Olive Oils From Sicilian Well-Known and Lesser-Known Cultivars.

Ali Mert Yetisgin, Giovanni Bartolomeo, Nicola Cicero, Nicola Micale, Rosaria Costa, Mariateresa Cristani

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. PreliminaryLife (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ali Mert YetisginFaculty of Pharmacy, İnönü University, Battalgazi, Malatya, Türkiye.
Giovanni BartolomeoDepartment of Biomedical, Dental, Morphological and Functional Images Sciences (BIOMORF), University of Messina, Messina, Italy.
Nicola CiceroDepartment of Biomedical, Dental, Morphological and Functional Images Sciences (BIOMORF), University of Messina, Messina, Italy.
Nicola MicaleDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.
Rosaria CostaDepartment of Biomedical, Dental, Morphological and Functional Images Sciences (BIOMORF), University of Messina, Messina, Italy.
Mariateresa CristaniDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.ORCID https://orcid.org/0000-0003-4689-9616

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the health benefits of extra virgin olive oils (EVOOs) from three different Sicilian cultivars, namely Nocellara del Belice, Ogliarola Messinese, and the lesser-known Verdello, grown in the regions of Agrigento and Messina. The quality parameters of the EVOOs, including free acidity, peroxide value, oxidation indices, and fatty acid composition, were first evaluated. Subsequently, the hydroalcoholic extracts of these oils (EVOOEs) were examined and their content of polyphenols was determined using HPLC and UV-vis spectrophotometry, as well as their antioxidant capacity (DPPH, ABTS, ORAC, and FRAP tests) and anti-inflammatory properties (COX-1/COX-2 inhibition assay) were also determined. The results showed significant qualitative and quantitative differences between cultivars: Nocellara and Verdello showed, in order, a higher content of both polyphenols (phenolic acids + flavonoids) than Ogliarola, correlated with a higher antioxidant activity profile and greater health-promoting potential. In addition, all extracts showed modest inhibition of COX-1 compared to COX-2, indicating potential selective anti-inflammatory effects. These results highlight the nutritional value of Sicilian EVOOs and the importance of cultivar selection. They also underscore the contribution of Sicilian olive oil production to dietary and therapeutic applications.

Indexed as

AntioxidantsDietary SupplementsOlive OilAnti-Inflammatory AgentsBiphenyl CompoundsChromatography, High Pressure LiquidCyclooxygenase 1Cyclooxygenase 2PicratesPolyphenolsSicilyAnti-Inflammatory AgentsAntioxidantsBiphenyl CompoundsCyclooxygenase 1Cyclooxygenase 2Olive OilPicratesPolyphenolsanti‐inflammatoryantioxidantcultivarsextra virgin olive oilpolyphenols

Identifiers

PMID42037524
PMCPMC13112324

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.