Evidence mapPaperPMID 42038031Full record

ReviewJournal of Cancer2026

Deciphering Cancer Therapy-Induced Cardiotoxicity in the Era of Spatial and Multi-Omics from Systemic Mechanisms to

Cheng Gou, Qian Li, Ting Xiong, Shengzheng Lin, Kaining Wang, Jianhao Liu, Chuansong Xue

Abstract readReview
In one paragraph

Review in Journal of Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cheng GouDivision of Cardiology, Guang'an People's Hospital, Guang'an, China.
Qian LiDepartment of Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ting XiongInternal Medicine of Three, Sanya Hospital of Traditional Chinese Medicine (Hainan Hospital, Guangzhou University of Chinese Medicine), Sanya, Hainan 572000, China.
Shengzheng LinInternal Medicine of Three, Sanya Hospital of Traditional Chinese Medicine (Hainan Hospital, Guangzhou University of Chinese Medicine), Sanya, Hainan 572000, China.
Kaining WangInternal Medicine of Three, Sanya Hospital of Traditional Chinese Medicine (Hainan Hospital, Guangzhou University of Chinese Medicine), Sanya, Hainan 572000, China.
Jianhao LiuInternal Medicine of Three, Sanya Hospital of Traditional Chinese Medicine (Hainan Hospital, Guangzhou University of Chinese Medicine), Sanya, Hainan 572000, China.
Chuansong XueInternal Medicine of Three, Sanya Hospital of Traditional Chinese Medicine (Hainan Hospital, Guangzhou University of Chinese Medicine), Sanya, Hainan 572000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardio-oncology has emerged as a critical discipline addressing the cardiovascular sequelae of antineoplastic therapies. While traditional chemotherapy, targeted therapies, and immune checkpoint inhibitors (ICIs) have revolutionized cancer survival, they are frequently accompanied by cardiotoxicity ranging from asymptomatic left ventricular dysfunction to fulminant myocarditis. Current clinical strategies, relying heavily on echocardiography and serum biomarkers, often fail to detect early molecular perturbations or elucidate the complex multicellular interactions within the cardiac microenvironment. The advent of multi-omics technologies, genomics, transcriptomics, proteomics, and metabolomics, has provided systemic insights into these pathomechanisms. More recently, the integration of single-cell RNA sequencing (scRNA-seq) and spatial omics has enabled "

Indexed as

Artificial IntelligenceCardio-oncologyMulti-omicsPrecision MedicineSpatial Transcriptomics

Identifiers

PMID42038031
PMCPMC13105155

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.