Evidence map›Paper›PMID 42038136›Full record

ReviewGalen medical journal2024

The Role of Mesenchymal Stem/Stromal Cells and Their Extracellular Vesicles in Rheumatoid Arthritis.

Amir Abaszadeh, Oveis Salehi, Ahmadreza Badali, Dorsa Lavanmardi, Alireza Sarlak, Azam Lotfalian, Maryam Poudineh

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Galen medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amir AbaszadehSchool of Medicine , Ilam University, Ilam, Iran.
Oveis SalehiTehran University of Medical Sciences, Tehran, Iran.
Ahmadreza BadaliTabriz University of Medical Sciences, Research Center for Connective Tissue Diseases.
Dorsa LavanmardiFars Stem Cell Research Institute, Shiraz, Fars, Iran.
Alireza SarlakStudent Research Committee, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Azam LotfalianDepartment of Biology and Anatomical Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Maryam PoudinehSchool of Medicine, Mashhad Azad University, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is presently no cure for the chronic inflammatory disease rheumatoid arthritis (RA), which affects the joints and other organs. Mesenchymal stem/stromal cells (MSCs) are adult stem cells that are widely studied in inflammatory diseases. Several studies have shown the therapeutic effects of MSCs in preclinical and clinical RA. However, there are a few concerns regarding the use of MSCs, such as immune rejection and malignancy. Since MSCs exert their potential effects in a paracrine manner, more attention has been paid to their extracellular vesicles (MSC-EVs). In the current study, we reviewed the application of MSCs and their EVs in RA. A better understanding of the mechanisms driving MSC and MSC-EVs in RA offers insight into possible treatment options for RA.

Indexed as

ExosomeExtracellular VesicleMesenchymal Stem CellRheumatoid Arthritis

Identifiers

PMID42038136
PMCPMC11827765

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.