Evidence map›Paper›PMID 42038749›Full record

ArticleHemaSphere2026

Pharmacological inhibition of sclerostin protects bone from B-cell acute lymphoblastic leukemia-mediated destruction.

Vincent Kuek, Joyce Oommen, Emanuela Ferrari, Jinbo Yuan, Aris N Economides, Richard B Lock, Sebastien Malinge, Rishi S Kotecha, Laurence C Cheung

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in HemaSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vincent KuekLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0003-2225-8566
Joyce OommenLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia Perth Western Australia Australia.
Emanuela FerrariLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia Perth Western Australia Australia.
Jinbo YuanSchool of Biomedical Sciences University of Western Australia Perth Western Australia Australia.
Aris N EconomidesRegeneron Pharmaceuticals Inc. Tarrytown New York United States.
Richard B LockChildren's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, UNSW Centre for Childhood Cancer Research, UNSW Sydney Sydney New South Wales Australia.ORCID https://orcid.org/0000-0002-3436-9071
Sebastien MalingeLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0002-9533-7778
Rishi S KotechaLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0003-1836-4075
Laurence C CheungLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0001-6298-5288

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42038749
PMCPMC13103727

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.