ArticleBiochemistry and biophysics reports2026
Oroxylin A ameliorates hepatic steatosis and non-alcoholic fatty liver disease through the regulation of CPT1A m
Article in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Non-alcoholic fatty liver disease (NAFLD) is a chronic condition that is frequently observed worldwide and has become a threat to global public health. Excess accumulation of hepatic lipids contributes to NAFLD. Oroxylin A has attracted widespread attention because of its antioxidant and immunomodulatory activities. Nonetheless, its role in hepatic lipid metabolism remains unclear. In this work, in hepatocytes exposed to palmitic acid (PA), oroxylin A significantly reduced lipid accumulation by inhibiting lipogenesis. Mechanistic studies revealed that oroxylin A can regulate m
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