Evidence map›Paper›PMID 42040186›Full record

ArticleCyborg and bionic systems (Washington, D.C.)2026

NIR-Propelled Biomimetic Nanomotors for Photothermal/Chemodynamic/NO Synergistic Tumor Therapy.

Ming Yang, Jian Hu, Zerui Li, Hanhan Xie, Hongri Gu, Chengzhi Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cyborg and bionic systems (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ming YangSchool of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, China.
Jian HuShenzhen Key Laboratory of Biomimetic Robotics and Intelligent Systems, Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen 518055, China.
Zerui LiShenzhen Key Laboratory of Biomimetic Robotics and Intelligent Systems, Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen 518055, China.
Hanhan XieSchool of Optoelectronic Engineering, Guangdong Polytechnic Normal University, Guangzhou 510665, China.
Hongri GuDivision of Integrative Systems and Design, Hong Kong University of Science and Technology, Hong Kong, China.
Chengzhi HuShenzhen Key Laboratory of Biomimetic Robotics and Intelligent Systems, Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen 518055, China.ORCID https://orcid.org/0000-0002-8627-2335

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multimodal nanotherapeutic systems capable of integrating photothermal, catalytic, and gas-mediated strategies offer powerful opportunities to overcome the limitations of single-mode cancer therapies. Here, we develop a near-infrared (NIR) light-activated biomimetic nanomotor for targeted nitric oxide (NO) delivery and synergistic cancer therapy. The nanomotor is constructed from bowl-shaped mesoporous polydopamine nanoparticles loaded with Fe(II) as a Fenton catalyst and BNN6 as a thermally responsive NO donor (denoted as PFB). To endow tumor specificity, the nanomotor is further camouflaged with MCF-7 cancer cell membrane (PFB@CM), enabling homologous recognition and enhanced intratumoral accumulation. Upon NIR irradiation, PFB@CM exhibits strong photothermal conversion efficiency that initiates 3 synergistic processes: (a) self-thermophoretic propulsion that promotes cellular internalization; (b) heat-triggered decomposition of BNN6 for precise NO release; and (c) heat-accelerated Fe(II) release from the polydopamine matrix. The liberated Fe(II) catalyzes endogenous H

Identifiers

PMID42040186
PMCPMC13106939

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.