Evidence map›Paper›PMID 42041567›Full record

ArticleCells2026

Astro-Versus Microglia-Enriched Transcriptomes from Aged

Georg Auburger, Arvind Reddy Kandi, Rajkumar Vutukuri, Luis-Enrique Almaguer-Mederos, Suzana Gispert, Nesli-Ece Sen, Jana Key

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Georg AuburgerExperimental Neurology, Clinic of Neurology, University Hospital, Goethe University Frankfurt, Heinrich-Hoffmann-Str. 7, 60528 Frankfurt am Main, Germany.
Arvind Reddy KandiExperimental Neurology, Clinic of Neurology, University Hospital, Goethe University Frankfurt, Heinrich-Hoffmann-Str. 7, 60528 Frankfurt am Main, Germany.ORCID 0000-0002-4020-1769
Rajkumar VutukuriInstitute of General Pharmacology and Toxicology, University Hospital, Goethe University Frankfurt, 60528 Frankfurt am Main, Germany.ORCID 0000-0002-7890-9471
Luis-Enrique Almaguer-MederosExperimental Neurology, Clinic of Neurology, University Hospital, Goethe University Frankfurt, Heinrich-Hoffmann-Str. 7, 60528 Frankfurt am Main, Germany.ORCID 0000-0003-0887-2359
Suzana GispertExperimental Neurology, Clinic of Neurology, University Hospital, Goethe University Frankfurt, Heinrich-Hoffmann-Str. 7, 60528 Frankfurt am Main, Germany.
Nesli-Ece SenExperimental Neurology, Clinic of Neurology, University Hospital, Goethe University Frankfurt, Heinrich-Hoffmann-Str. 7, 60528 Frankfurt am Main, Germany.
Jana KeyExperimental Neurology, Clinic of Neurology, University Hospital, Goethe University Frankfurt, Heinrich-Hoffmann-Str. 7, 60528 Frankfurt am Main, Germany.

Funding

Deutsche Forschungsgemeinschaft AU96/21-1Deutsche Forschungsgemeinschaft SFB1039
6 · The paper itself

Abstract

Spinocerebellar Ataxia type 2 (SCA2) and Amyotrophic Lateral Sclerosis type 13 (ALS13) are triggered by polyglutamine expansion in Ataxin-2 (ATXN2). To understand these neurodegenerative disorders at the molecular level, the brains of 10-month-old

Indexed as

AgingAtaxin-2MicrogliaRibosomesTranscriptomeAnimalsMiceAtaxin-2Atxn2 protein, mousefractionation controls Aif1, Gfap, Map2, Cldn5Miltenyi MACS adult brain separatormRNA circularizationneurofilament lossRNA-seqSTRING enrichment bioinformaticstranslation dynamicsU1 3′ stem-loop structure recognition by SMNuridine-rich small nuclear RNA

Identifiers

PMID42041567
PMCPMC13115098

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.