Evidence map›Paper›PMID 42041865›Full record

ArticleJournal of xenobiotics2026

SPE-UHPLC-MS/MS Method for Simultaneous Quantification of 50 Pesticide Biomarkers Across Nine Current-Use Chemical Classes in Human Urine.

Ravikumar Jagani, Jasmin Chovatiya, Hiraj Patel, Sandipkumar Teraiya, Divya Pulivarthi, Syam S Andra

Abstract read
In one paragraph

Article in Journal of xenobiotics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ravikumar JaganiInstitute for Exposomic Research, Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-7680-860X
Jasmin ChovatiyaInstitute for Exposomic Research, Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0009-0007-9925-7795
Hiraj PatelInstitute for Exposomic Research, Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0009-0007-8973-4375
Sandipkumar TeraiyaInstitute for Exposomic Research, Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Divya PulivarthiInstitute for Exposomic Research, Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Syam S AndraInstitute for Exposomic Research, Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-2839-6417

Funding

Untargeted Analysis ResourceU2CES026561 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROBERT O · 2015 to 2025
$24.5M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Chris Gennings · 2014 to 2026
$21.3M
Untargeted Analysis ResourceU2CES030859 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ARORA, MANISH · 2019 to 2025
$8.2M
NIEHS NIH HHS P30 ES023515NIEHS NIH HHS U2C ES026561NIEHS NIH HHS U2C ES030859
6 · The paper itself

Abstract

A comprehensive ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method was developed for the simultaneous quantification of 50 pesticide biomarkers across nine current-use chemical classes in human urine. These classes include organophosphorus insecticides (which encompass dialkyl phosphates and specific metabolites), pyrethroid insecticides, fungicides, neonicotinoid insecticides, herbicides, insect repellents, organochlorine pesticide metabolites, and plant growth regulators. The method employs solid-phase extraction (SPE) for sample preparation, requiring only 0.2 mL of urine. Chromatographic separation was optimized using a Hypersil Gold AQ column, achieving a total run time of 18 min. Mass spectrometric detection utilized polarity switching in electrospray ionization mode with multiple reaction monitoring. Method validation demonstrated satisfactory linearity (R

Indexed as

Exposomicshuman biomonitoringmulti-class analysispesticide biomarkerssolid-phase extractionUHPLC–MS/MS

Identifiers

PMID42041865
PMCPMC13117499

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.