Treatment of Mesenchymal Stem Cell-Derived Extracellular Vesicles with Extract of Cultured

Farzaneh Sharifzad, Nawal Alsadi, Hamed Yasavoli-Sharahi, Roghayeh Shahbazi, Dylan Burger, Chantal Matar

Abstract read

In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farzaneh SharifzadSchool of Nutrition Sciences, Faculty of Health Sciences, University of Ottawa, Ontario, ON K1N 6N5, Canada.ORCID 0000-0002-7959-4440

Nawal AlsadiSchool of Nutrition Sciences, Faculty of Health Sciences, University of Ottawa, Ontario, ON K1N 6N5, Canada.

Hamed Yasavoli-SharahiSchool of Nutrition Sciences, Faculty of Health Sciences, University of Ottawa, Ontario, ON K1N 6N5, Canada.

Roghayeh ShahbaziSchool of Nutrition Sciences, Faculty of Health Sciences, University of Ottawa, Ontario, ON K1N 6N5, Canada.

Dylan BurgerDepartment of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ontario, ON K1N 6N5, Canada.ORCID 0000-0003-3951-2911

Chantal MatarSchool of Nutrition Sciences, Faculty of Health Sciences, University of Ottawa, Ontario, ON K1N 6N5, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast carcinoma represents the most frequent malignancy in women in Canada, and intrinsic or acquired drug resistance significantly increases the risk of recurrence and metastasis. Although front-line therapy is multimodal, chemoresistance remains a major hurdle in treatment and therapy, and the intake of natural compounds resulting from fermentation processes is currently considered an effective strategy to overcome this problem. This study investigated the effect of extracellular vesicles (EVs) from Mesenchymal Stromal/stem cells (MSCs) pretreated with cultured

Indexed as

cancer stem cellsextracellular vesicleLentinula edodesmesenchymal stem cellmicroRNAs

Identifiers

PMID42042028

DOI10.3390/cimb48040368

PMCPMC13114336

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.