Evidence map›Paper›PMID 42042291›Full record

ReviewJournal of functional biomaterials2026

Advances and Challenges in Tissue Engineering: Biomaterials, Cellular Strategies, and Clinical Applications.

Rosana Farjaminejad, Samira Farjaminejad, Franklin Garcia-Godoy, Anand Marya, Ludovica Nucci, Abdolreza Jamilian

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rosana FarjaminejadDepartment of Health Services Research and Management, School of Health and Psychological Sciences, City, University of London, London WC1E 7HU, UK.ORCID 0009-0006-7795-0444
Samira FarjaminejadDepartment of Health Services Research and Management, School of Health and Psychological Sciences, City, University of London, London WC1E 7HU, UK.ORCID 0009-0001-8339-0272
Franklin Garcia-GodoyDepartment of Bioscience Research, Bioscience Research Centre, College of Dentistry, University of Tennessee Health Science Centre, 875 Union Avenue, Memphis, TN 38163, USA.ORCID 0000-0001-8133-3306
Anand MaryaDental School, University of Greater Manchester, Bolton BL3 5AB, UK.ORCID 0000-0003-2009-4393
Ludovica NucciDepartment of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.
Abdolreza JamilianDental School, University of Greater Manchester, Bolton BL3 5AB, UK.ORCID 0000-0002-8841-0447

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering integrates concepts from medicine, biology, and engineering to create living constructs capable of repairing, replacing, or supporting damaged tissues. This multidisciplinary field relies on the interplay between biomaterials, cellular sources, and bioactive signaling to achieve functional tissue regeneration. This review provides a comprehensive overview of recent advances in scaffold design, highlighting natural, synthetic, and hybrid materials, as well as innovative fabrication techniques such as electrospinning, 3D bioprinting, and smart biomaterials. It discusses the role of stem cells and growth factors in directing regeneration and examines a wide range of clinical applications, including skin regeneration, cartilage repair, bone tissue engineering, dental and periodontal regeneration, nerve repair, cardiac tissue engineering, liver tissue models, and ophthalmic applications. Current challenges, such as immune responses, limited vascularization, scalability, and regulatory barriers, are addressed alongside emerging strategies aimed at improving clinical translation. By integrating diverse tissue types and engineering approaches within a unified framework, this review offers a broad yet detailed perspective on the current state and future directions of regenerative medicine.

Indexed as

bone tissue engineeringcardiac tissue engineeringcartilage tissue engineeringdental tissue engineeringliver tissue engineeringnerve tissue engineeringophthalmic tissue engineeringskin tissue engineeringtissue engineering (TE)

Identifiers

PMID42042291
PMCPMC13118247

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.