Evidence map›Paper›PMID 42042866›Full record

ReviewMetabolites2026

Pleiotropic Cholesterol Signaling in

Yueyang Kang, Muhammad Atif, Youngseok Lee

Abstract readReview
In one paragraph

Review in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Natural Plant Extracts Rescue Memory Deficits inJournal of microbiology and biotechnology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yueyang KangDepartment of Integrative Biotechnology, Kookmin University, Seoul 02707, Republic of Korea.
Muhammad AtifDepartment of Integrative Biotechnology, Kookmin University, Seoul 02707, Republic of Korea.
Youngseok LeeDepartment of Integrative Biotechnology, Kookmin University, Seoul 02707, Republic of Korea.ORCID 0000-0003-0459-1138

Funding

National Research Foundation of Korea RS-2026-25483541
6 · The paper itself

Abstract

Growth, reproduction, and survival are fundamental biological priorities that animals balance by evaluating dietary cues. Cholesterol occupies a unique position among nutrients, serving both as a structural component of cellular membranes and as a precursor for steroid hormones, yet its regulation differs fundamentally across taxa. In mammals, cholesterol availability is buffered by endogenous synthesis and post-ingestive metabolic control. In contrast, insects have evolutionarily lost sterol biosynthesis and are therefore sterol auxotrophs that rely entirely on dietary sources. Here, we synthesize current understanding of cholesterol biology in

Indexed as

cholesterolfeeding behaviornutrient sensingsterol auxotrophy

Identifiers

PMID42042866
PMCPMC13118006

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.