Evidence map›Paper›PMID 42043154›Full record

ReviewToxics2026

ABCG2 Genetic Variability in Drug Exposure and Toxicity: Implications for Clinical Practice.

Tamara Božina, Livija Šimičević, Lana Ganoci, Mila Lovrić, Iva Klarica Domjanović, Vladimir Trkulja, Nada Božina

Abstract readReview
In one paragraph

Review in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tamara BožinaDepartment for Chemistry and Biochemistry, University of Zagreb School of Medicine, Šalata 3, 10000 Zagreb, Croatia.ORCID 0000-0001-5883-7979
Livija ŠimičevićDepartment for Chemistry and Biochemistry, University of Zagreb School of Medicine, Šalata 3, 10000 Zagreb, Croatia.ORCID 0000-0002-2491-1920
Lana GanociDivision for Pharmacogenomics and Therapy Individualization, Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.ORCID 0000-0003-3898-4554
Mila LovrićDepartment for Chemistry and Biochemistry, University of Zagreb School of Medicine, Šalata 3, 10000 Zagreb, Croatia.
Iva Klarica DomjanovićCroatian Agency for Medicinal Products and Medical Devices, Ksaverska Cesta 4, 10000 Zagreb, Croatia.
Vladimir TrkuljaDepartment of Basic and Clinical Pharmacology, University of Zagreb School of Medicine, Šalata 3, 10000 Zagreb, Croatia.ORCID 0000-0002-0968-1194
Nada BožinaDepartment of Basic and Clinical Pharmacology, University of Zagreb School of Medicine, Šalata 3, 10000 Zagreb, Croatia.

Funding

Croatian Science Foundation. Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction (PGx-CardioDrug) HRZZ-UIP-2020-02-8189.
6 · The paper itself

Abstract

The ATP-binding cassette subfamily G member 2 (ABCG2), also known as breast cancer resistance protein (BCRP), is an efflux transporter expressed in key pharmacokinetic tissues and biological barriers. It regulates exposure to many endogenous compounds, drugs, and environmental toxins. Genetic variability in

Indexed as

ABCG2 proteinATP-binding cassette transportersdrug interactionsdrug-related side effects and adverse reactionsdrug transporterspharmacogeneticspolygenic risk scoreprecision medicine

Identifiers

PMID42043154
PMCPMC13120264

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.