Evidence map›Paper›PMID 42043636›Full record

SynthesisEndocrine2026

Effects of Low-Fat Diet Combined with Different Exercise Interventions on Weight Loss Maintenance in Adults: A Network Meta-Analysis.

Xiaohong Wu, Qi Liu, Weiping Zhong, Lulin Zhang, Zhixiang Xu, Lianyu Fan, Jieping Zhu, Liqiang Su

Abstract readNetwork Meta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Endocrine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaohong WuSchool of Physical Education, Jiangxi Normal University, Nanchang, 330022, China.ORCID http://orcid.org/0009-0006-9611-1101
Qi LiuSchool of Physical Education, Jiangxi Normal University, Nanchang, 330022, China.
Weiping ZhongSchool of Physical Education, Jiangxi Normal University, Nanchang, 330022, China.
Lulin ZhangSchool of Physical Education, Jiangxi Normal University, Nanchang, 330022, China.
Zhixiang XuSchool of Physical Education, Jiangxi Normal University, Nanchang, 330022, China.
Lianyu FanSchool of Physical Education, Jiangxi Normal University, Nanchang, 330022, China.
Jieping ZhuSchool of Physical Education, Jiangxi Normal University, Nanchang, 330022, China.
Liqiang SuSchool of Physical Education, Jiangxi Normal University, Nanchang, 330022, China. s-2005100153@163.com.

Funding

Jiangxi Provincial Social Science Planning Project 25TY07This work was supported by the National Key R&D Program of China no. 2024YFC3607302
6 · The paper itself

Abstract

objectiveThis study aims to synthesize relevant randomized controlled trials (RCTs) via network meta-analysis (NMA) to identify the most effective “low-fat diet + exercise” intervention for adult weight maintenance.

methodsUp to January 2026, five databases were searched for RCTs on exercise-diet combinations. Literature quality was assessed using the Cochrane tool, random-effects analysis was conducted for each intervention, and NMA was performed to compare their weight loss maintenance efficacy.

results9 RCTs involving 1,207 participants were included, comparing 5 interventions. All interventions showed weight reduction trends vs. the control group (CON), but their 95% confidence intervals were wide and crossed zero, with no statistical significance. Anaerobic resistance exercise (ARE) had the highest ranking probability (SUCRA: 65.2), with a body weight (BW) mean difference of -0.86 (95% CI: [-3.33, 1.60]).

conclusionAll interventions tended to reduce weight, with ARE ranking highest. However, due to imprecise effect estimates, this result is exploratory.

Indexed as

Body Weight MaintenanceDiet, Fat-RestrictedExerciseExercise TherapyObesityWeight LossAdultHumansRandomized Controlled Trials as Topicexerciselow-fat dietnetwork meta-analysisobesityweight loss maintenance

Identifiers

PMID42043636

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.