Evidence map›Paper›PMID 42043708›Full record

ArticleInsights into imaging2026

Non-invasive ultrasound assessment of chronic liver disease: current position and future directions for a "one-stop" liver ultrasound approach.

Paul S Sidhu, Mustafa Secil, Dirke-Andre Clevert, Adrian K P Lim, Maciej Piskunowicz, Paolo Ricci, Thomas Fischer, Vladimir Mitkov, Vito Cantisani, Caroline Ewersten and 1 more

Abstract read
In one paragraph

Article in Insights into imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Paul S SidhuDepartment of Imaging Sciences, School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Mustafa SecilDepartment of Radiology, Faculty of Medicine, Dokuz Eylul University, İzmir, Türkiye.
Dirke-Andre ClevertInterdisciplinary Ultrasound-Center, Department of Radiology, University of Munich, Grosshadern Campus, Munich, Germany.
Adrian K P LimDepartment of Imaging, Imperial College Healthcare NHS Trust & Department of Digestive Diseases, Reproduction and Metabolism, Imperial College London, London, UK.
Maciej PiskunowiczRadiology Department, Medical University of Gdansk, Gdansk, Poland.
Paolo RicciUnit of Emergency Radiology, AOU Policlinico Umberto 1 & Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy.
Thomas FischerDepartment of Radiology, Interdisciplinary Ultrasound Center, Campus Charité Mitte, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Vladimir MitkovDiagnostic Ultrasound Department, Russian Medical Academy of Continuous Professional Education, Moscow, Russia.
Vito CantisaniBessa Department University Sapienza of Rome, Rome, Italy.
Caroline EwerstenDepartment of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
European Society of Radiology (ESR)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of the multitude of ultrasound techniques into a "one-stop" liver clinic model will revolutionize the management of liver diseases. This approach streamlines patient care by providing immediate imaging assessment, facilitating prompt diagnosis, and expediting treatment plans. The traditional ultrasound methods of B-mode imaging and Doppler techniques have been supplemented by the newer techniques of tissue elastography, fat quantification, and contrast-enhanced ultrasound-termed multiparametric ultrasound. The deployment of these techniques to establish in more detail the underlying status of liver disease has been profound. The encompassing ultrasound techniques have allowed the ultrasound practitioner to establish a comprehensive assessment of liver disease, allowing further accurate management, and negating the need for additional, often more expensive, imaging to establish the diagnosis. This paper explores the implementation, benefits, and challenges of ultrasound-based one-stop liver clinics, emphasizing their impact on patient outcomes and healthcare efficiency. A detailed assessment of the techniques and their position in the diagnostic armamentarium is reviewed with a comprehensive overview established. CRITICAL RELEVANCE STATEMENT: Multiparametric liver ultrasound integrating B-mode, Doppler, CEUS, elastography and fat quantification provides a practical, low-cost one-stop pathway for staging chronic liver disease, assessing portal hypertension surrogates and characterizing incidental lesions, thereby speeding up treatment. KEY POINTS: Ultrasound is the first-line imaging investigation for liver disease, with established criteria on B-mode imaging for steatosis and cirrhosis. Multiparametric ultrasound integrates morphology, hemodynamics, fibrosis, steatosis, and lesion assessment. A one-stop liver ultrasound clinic accelerates decisions and reduces additional imaging.

Indexed as

Chronic liver diseaseContrast enhanced ultrasoundElastographyFat quantificationUltrasonography

Identifiers

PMID42043708
PMCPMC13121678

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.