ArticleEuropean geriatric medicine2026
Association between oral frailty and a laboratory-based frailty index in older adults.
Article in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
purposeTo examine the association between oral frailty and laboratory-based Frailty Index (FI-lab) in older adults.
methodsThis cross-sectional study included patients aged ≥ 65 years who attended a frailty outpatient clinic. Oral frailty was assessed using the Oral Frailty five-item checklist. The FI-lab was constructed from 31 laboratory parameters, with frailty defined as an FI-lab value > 0.21. The association between oral frailty and FI-lab-defined frailty was examined using multivariable logistic regression analysis.
resultsAmong the 486 patients, the mean age was 77.9 ± 6.3 years, and 63.6% were women. The prevalence of oral frailty was 49.6%, and the median FI-lab value was 0.16. Oral frailty was significantly associated with FI-lab-defined frailty after adjustment for age, sex, and comorbidities (odds ratio 1.52, 95% confidence interval 1.01-2.29).
conclusionOral frailty is associated with FI-lab-defined frailty, suggesting a relationship between oral function and latent physiological vulnerability, as captured by the FI-lab.
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