Trial reportEuropean journal of applied physiology2026
Impact of body mass index on blood pressure and cardiovascular adaptation to isometric exercise training.
Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesObesity is characterised by excess adipose tissue, which impairs vascular function and blood pressure (BP) regulation. However, it remains unclear whether adiposity influences the BP-lowering response to isometric exercise training (IET). This randomised-controlled trial explored the impact of body mass index on BP and cardiovascular adaptation following IET.
methods80 participants with normal to high-normal systolic BP (range 120-140 mmHg) were recruited for the study. Participants were randomised into two BMI groups: normal BMI (18.5-24.9 kg/m²; n=40) and high BMI (25-34.9 kg/m²; n=40) and then either performed home-based lower-body IET, 3 times per week, for 4 weeks (each session comprised 4 x 2-minute bouts), or were allocated to the control group. Cardiovascular variables, including BP, total peripheral resistance (TPR), and heart rate variability (HRV), were measured at rest pre- and post-intervention.
resultsOverall, there were significant reductions in systolic BP, diastolic BP and mean arterial pressure (MAP) in the IET group compared to control. However, the normal-BMI group had significantly greater reductions in diastolic BP (- 8.5 [- 11.8, - 5.3] mmHg) and MAP (- 9.2 [- 11.9, - 6.6] mmHg) compared to the high-BMI group (dBP: - 2.6 [- 6.2, 1.1]; MAP: -4.7 [- 7.6, - 1.8]). Although TPR was significantly greater in the high-BMI group at week 4 (p=0.022), it was also elevated at baseline, and change-score analyses revealed no significant between-group difference in the magnitude of TPR reduction (Δ p=0.964).
conclusionThese findings indicate that BMI may modulate the BP-lowering response to IET, suggesting that individuals with higher BMI may require adjunctive or prolonged interventions to optimise BP reduction.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.