Evidence mapPaperPMID 42048404Full record

ArticlePLoS medicine2026

The principles of Population-Level Approaches to Dementia Risk Reduction (PLADRR).

Sebastian Walsh, Susanne Röhr, Joaquin Mígeot, Yuliya Bodryzlova, Etuini Ma'u, Simone Salemme, Charles R Marshall, Timothy Daly, Gary Cheung, Blossom C M Stephan and 21 more

Abstract read
In one paragraph

Article in PLoS medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. From mapping evidence to engaging voices: Paving the way for research on the social determinants of dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Sebastian WalshCambridge Public Health, Hershel Smith Building, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0001-8894-5006
Susanne RöhrCentre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, Australia.
Joaquin MígeotGlobal Brain Health Institute (GBHI), Trinity College Dublin, Dublin, Ireland.
Yuliya BodryzlovaDépartement de médecine sociale et préventive, Université Laval, Quebec City, Canada.
Etuini Ma'uDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0003-3989-8404
Simone SalemmeDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.ORCID https://orcid.org/0000-0002-9260-9993
Charles R MarshallCentre for Preventive Neurology, Queen Mary University of London, London, United Kingdom.
Timothy DalyBioethics Program, FLACSO Argentina, Buenos Aires, Argentina.
Gary CheungDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
Blossom C M StephanDementia Centre of Excellence, Curtin enAble Institute, Curtin University, Perth, Australia.
Raj KalariaClinical and Translational Research Institute, Newcastle University, Newcastle, United Kingdom.
Kenneth M LangaDepartment of Internal Medicine and Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America.ORCID https://orcid.org/0000-0002-2798-1836
Naaheed MukadamUCL Division of Psychiatry, Maple House, London, United Kingdom.ORCID https://orcid.org/0000-0001-8635-9521
Leslie GrassetBordeaux Population Health, Université de Bordeaux & INSERM, UMR 1219, Bordeaux, France.
Sarah CullumGlobal Brain Health Institute (GBHI), Trinity College Dublin, Dublin, Ireland.
Ishtar GoviaAmagi Health Ltd, London, England.
Nikki-Anne WilsonSchool of Psychology, Faculty of Science, University of New South Wales, Mathews Building, UNSW Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0003-1655-5927
Daniele UrsoCenter for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', Tricase, Italy.ORCID https://orcid.org/0000-0002-4503-0110
Ruth PetersThe George Institute for Global Health Australia, Sydney, Australia.ORCID https://orcid.org/0000-0003-0148-3617
Jingxuan WangDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0002-9387-0480
Edo RichardDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands.
Giancarlo LogroscinoCenter for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', Tricase, Italy.
Stefano Giannoni-LuzaCenter for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', Tricase, Italy.ORCID https://orcid.org/0000-0001-7413-4501
Nicola T LautenschlagerDepartment of Psychiatry, The University of Melbourne, Melbourne, Australia.
Josephine E PrynnDepartment of Population Health Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-5275-8644
Cleusa P FerriDepartment of Psychiatry, Old Age Psychiatry Unit, Universidade Federal de Sao Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-1815-7685
Susan YatesCentre for Brain Research, University of Auckland, Auckland, New Zealand.
Frank J WoltersDepartment of Epidemiology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-2226-4050
Lindsay WallaceDepartment of Community Health & Epidemiology, Faculty of Medicine, Dalhousie University, Halifax, Canada.
Carol BrayneCambridge Public Health, Hershel Smith Building, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0001-5307-663X
Kaarin J AnsteySchool of Psychology, Faculty of Science, University of New South Wales, Mathews Building, UNSW Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0002-9706-9316

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dementia is a leading health policy challenge, with cases expected to triple by 2050, particularly in low- and middle-income countries. Epidemiological evidence demonstrates falling age-specific incidence rates in high-income countries, suggesting risk can be lowered at the population level.The Population-Level Approaches to Dementia Risk Reduction (PLADRR) Research Group is a diverse, international network of researchers committed to investigating how structural, social, and environmental conditions can promote life course brain health and reduce dementia risk across the population.This Policy Forum article sets out the guiding principles of our approach, the building blocks required, our research priorities, and how PLADRR research can inform and translate into policy changes.

Indexed as

DementiaRisk Reduction BehaviorHealth PolicyHumansRisk Factors

Identifiers

PMID42048404
PMCPMC13123963

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.